Medicine

WHO Declares End To COVID Global Health Emergency (reuters.com) 146

The World Health Organization ended the global emergency status for COVID-19 on Friday more than three years after its original declaration, and said countries should now manage the virus that killed more than 6.9 million people along with other infectious diseases. From a report: The global health agency's Emergency Committee met on Thursday and recommended the UN organization declare an end to the coronavirus crisis as a "public health emergency of international concern" -- its highest level of alert -- which has been in place since Jan. 30, 2020. "It is therefore with great hope that I declare COVID-19 over as a global health emergency," said WHO Director-General Tedros Adhanom Ghebreyesus, adding that the end of the emergency did not mean COVID was over as a global health threat. During a lengthy conference call to brief the press on the decision, some WHO members became emotional as they urged countries to reflect on lessons learned during the pandemic.
Medicine

How Our Brutal Science System Almost Cost Us a Pioneer of mRNA Vaccines (wbur.org) 116

Long-time Slashdot reader theodp writes: As the first COVID-19 vaccines arrived at Penn Medicine last year, Penn Today reported with great pride, "It was mRNA research conducted at Penn—by Drew Weissman, a professor of Infectious Diseases, and Katalin Karikó, an adjunct associate professor—that helped pave the way for the development of the Pfizer-BioNTech and Moderna COVID vaccines." While Weissman and Karikó are coronavirus vaccine heroes these days, Dr. David Scales — who studied under Weissman and Karikó 20 years ago as they worked on mRNA vaccines aimed to fight HIV — recalls How Our Brutal Science System Almost Cost Us A Pioneer Of mRNA Vaccines.

"When I got my own [COVID vaccine] shot," Scales writes, "I felt an added emotion: awe. You see, I witnessed some of the early scientific heartbreaks that came before the historic vaccine victories. And I found myself simply awestruck by the scientists I knew who persevered in spite of our system of scientific research. [...] While Weissman was an expert at designing experiments, I remember him most for his generosity. He made sure all contributors in the lab shared the credit, from the lab tech and lowly undergrad all the way to fellow researcher Karikó. Still, Karikó was struggling. Her science was fantastic, but she was less adept at the competitive game of science. She tried again and again to win grants, and each time, her applications were rejected. Eventually, in the mid-1990s, she suffered the academic indignity of demotion, meaning she was taken off the academic ladder that leads to becoming a professor. [...] But [Karikó] stuck to her passions. She was too committed to the promise of mRNA to switch to other, perhaps more easily fundable projects. Eventually, the university stopped supporting her."

"Academic science failed Karikó. But when she contacted me in 2015, I saw she had moved to the private sector, a common path for researchers when a university stops offering support. I was glad to see she had landed on her feet. And now, I watch in awe, like the rest of the world, as the technology she helped developed leads to one of the most spectacular victories in the history of science — a vaccine for a deadly pandemic developed in less than one year. So, my vaccination day was an emotional one. As the lipid-encapsulated mRNA molecules went into my arm, I reminisced about Kati and Drew, and the lab circa 2000. And I thought: You were right, Kati. You were right."

Robotics

The 'Robotic Psychiatrist' Answers 144

Joanne Pransky's tongue is firmly in her cheek a fair amount of the time as she answers your questions, but much of what she says is thought-provoking, especially in light of speculations like Marshall Brain's Robotic Nation essays about the inevitable spread of robotic devices in our society.

Frankenstein Time 654

Despite the soothing caveats about ethical standards, staving off discrimination and privacy issues, the completion of the so-called human map offers benefits and nightmares in almost equal proportions. Once unleashed, powerful technologies are tough to contain or control. There was lots of megahype chatter about curing cancer, heart disease and aging, but this is now officially Frankenstein time, the era of the "perfect baby" and human quality control. Unfortunately for the world, it's hard to imagine a more poorly equipped society to deal with the Human Genome Project than the U.S.
Science

The Genome Project and the Dark Side 556

The Human Genome Project, often referred to on this site, may be the most inspiring and disturbing technological project in contemporary history. It embodies the often tragic drama of contemporary technology: well-meaning people trying in the noblest way to improve the world; setting in motion forces few ordinary people understand, agree upon or are prepared for.
News

Sexbots 1

Engineers, programmers and futurists believe that programmable robots that provide sexual companionship are likely to be commonplace in the 21st century, at more or less the same time as computers become able to process information as quickly as the human brain. The implications of tactile sexbots, likely to contain vibrators, sound systems and other equipment, are as significant as they are unexamined. If you thought the fight over the CDA was bad, wait till Rev. Falwell and his many pious friends in Congress discover Sexbots. For better or worse, computing might be breaking down another big wall.

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