"Can you skydive continuously without landing...?" asks Red Bull. Imagine jumping out of a helicopter, "only to latch onto a speeding plane in mid-air and soar back up into the sky." Harnessing the plane's momentum, [skydiver Max Manow] soared out of the canyon, embarking on what he calls his "endless skydive", a manoeuvre that potentially could be done continuously without him ever needing to land...

After exiting a helicopter, he manoeuvred his wingsuit to close the gap with a nosediving Cessna 182, piloted by Luke Aikins. Precision was key: Manow attached himself to a hook on the aircraft as the plane descended, allowing him to ascend back to a safe altitude of 2,500 feet before releasing into another freefall... Manow spent five months training, including sessions in a Stockholm wind tunnel, to master the techniques needed for mid-air connection. Meanwhile, Aikins modified his aircraft to ensure the feat was safe and repeatable.

Skydiver Max Manow's goal was to develop a manoeuvre that could potentially be repeated an infinite number of times without ever having to land. Manow's mid-air manoeuvre opens the door to a new vision of skydiving, where athletes could remain airborne without ever needing to land. Reflecting on the experience, Manow said: "Who knows where this will take the future of the sport?"
"If that wasn't enough adrenaline for you," writes New Atlas, "a previous bonkers wingsuit stunt from 2017 is equally jaw dropping, in which a pair of skydivers BASE-jumped off a mountain summit, and entered a passing airplane."

As AMD is now well into their third generation of RDNA architecture GPUs, the sun has been slowly setting on AMD's remaining Graphics Core Next (GCN) designs, better known by the architecture names of Polaris and Vega. From a report: In recent weeks the company dropped support for those GPU architectures in their open source Vulkan Linux driver, AMDVLK, and now we have confirmation that the company is slowly winding down support for these architectures in their Windows drivers as well. Under AMD's extended driver support schedule for Polaris and Vega, the drivers for these architectures will no longer be kept at feature parity with the RDNA architectures. And while AMD will continue to support Polaris and Vega for some time to come, that support is being reduced to security updates and "functionality updates as available."

For AMD users keeping a close eye on their driver releases, they'll likely recognize that AMD already began this process back in September -- though AMD hasn't officially documented the change until now. As of AMD's September Adrenaline 23.9 driver series, AMD split up the RDNA and GCN driver packages, and with that they have also split the driver branches between the two architectures. As a result, only RDNA cards are receiving new features and updates as part of AMD's mainline driver branch (currently 23.20), while the GCN cards have been parked on a maintenance driver branch - 23.19.

An anonymous reader quotes a report from Bloomberg: When Nestle SA's peanut allergy medicine first hit the market in 2020, Robert Wood, the director of pediatric allergy at Johns Hopkins Hospital in Baltimore, started preparing to offer it to the children he treats. But Covid-19 soon derailed in-person treatment, so over the next year and a half Wood and his colleagues told some 1,000 patients about the new drug instead, suggesting they consider it when the pandemic abated. Their responses came as a shock. Only six people were interested in a medicine that had been billed as a game changer for life-threatening allergies -- the first of its kind to be cleared by US authorities. Three years later, Wood has yet to prescribe the drug, Palforzia, and he isn't alone. Doctors and patients from California to Germany appear to be shunning the medicine in favor of the tried-and-true prescription for sufferers: simply avoiding peanuts and carrying an adrenaline injection for emergencies.

Nestle's chief executive officer, Mark Schneider, admitted as much in November, conceding that the drug's uptake had been slow. Schneider in 2020 bought out Palforzia's developer for $2.6 billion, paying a staggering 174% premium as he sought to take "the science business to the next level," snapping up vitamin makers such as Puritan's Pride and Solgar as well. The company is looking for a buyer, and the Swiss food giant says it will have to recognize a significant impairment to the deal's original value -- likely presaging a big writedown at a time when its core grocery business faces pressure from inflation. Maybe the company known for Nespresso capsules and Kit Kat chocolate wafers was never the right owner for a complex-to-administer niche medicine, but Schneider is on the hunt to find new avenues of growth in keeping with his strategic tilt toward health and wellness. The CEO "is looking to make acquisitions in new areas, and that inherently carries risks," says Martin Deboo, an analyst at Jefferies. "Palforzia is a signal of that." Nestle reiterated its commitment to nutritional health in an email and said Palforzia is safe and effective and solves the problem of variable potency that can hobble efficacy or trigger an allergic reaction with other less stringent treatments.

The product is essentially peanut protein that's been packed in a pill, standardized and categorized as a medicine after meeting the Food and Drug Administration's exacting clinical-trial requirements on safety and efficacy. By exposing children to tiny but gradually increasing amounts of the ingredient, Palforzia slowly raises their sensitivity threshold. But the process requires commitment by parents and kids to a demanding regime that lasts more than a year. [...] Palforzia is not without risk. During the clinical trials, about 9% of children suffered potentially dangerous immune reactions when their doses were being increased. [...] Bloomberg notes that Germany's Institute for Quality and Efficiency in Health Care concluded that Nestle's drug "doesn't offer any advantage over peanut avoidance." A UK panel that assess medicines' cost-effectiveness also found the drug to be quite expensive, costing about $6,220 per patient in England.

"As for Wood at Johns Hopkins, he says the allergy center would've lost money administering Palforzia -- something it was willing to do if there had been enough interest among patients. When asked whether some patients might've gone elsewhere for Palforzia, Wood says probably not."

A Philadelphia mother has given birth to what is believed to be the world's first Tesla baby: an infant delivered in the front seat of an electric smart car while it was driving on autopilot. From a report: The remarkable delivery, reported by the Philadelphia Inquirer, took place in September while Yiran Sherry, 33, and her husband Keating Sherry, 34, were taking their three-year-old son Rafa to pre-school. Yiran Sherry's waters broke while the family was stuck in traffic. With contractions increasing rapidly and traffic barely moving, the couple realized they were not going to make it in time.

Keating Sherry placed the vehicle on autopilot after setting the navigation system to the hospital, 20 minutes away in the western suburb of Paoli. He said he laid one hand gently on the car's steering wheel as he attended to his wife. "She was squeezing my hand to the point where I thought she was going to shatter it," Keating Sherry told the Inquirer. "I was [saying] 'Yiran, OK, focus on your breathing.' That was advice to myself, as well. My adrenaline was pumping." Yiran Sherry said the decision over whether to try to wait to give birth until they reached the hospital was an agonising one. However, she said, she kept glancing at their estimated arrival time and saw it was barely moving.

DevNull127 writes: You probably remember Zoe Bell strapped to the hood of a speeding 1970 Dodge Challenger in the Death Proof half of Quentin Tarantino's Grindhouse. (She also had parts in The Hateful Eight and Once Upon a Time in Hollywood.) Today Zoe pulled together what may become a historic video — a massive online collaboration with 40 different film celebrities [and also some stuntpeople] that one reporter called "a stunning display of stunt, editing and acting skills — all put together without anyone collaborating in-person."

Deadline explains:
The most badass actresses and stuntwomen of Hollywood had a full-out, virtual battle royale thanks to actress and stuntwoman extraordinaire Zoe Bell and her video appropriately titled Boss Bitch Fight Challenge. "I'm so bored! I just want to play with my friends!" she proclaims as it is clear she wants to liven things up during her quarantine. What happens next is over five minutes of virtual fisticuffs.

It's a real adrenaline-booster, and Deadline's article also has a complete list of each star appearing in the video.
That list is like revisiting the history of Hollywood action films over the last 20 years. It includes:

• Lucy Lawless (Xena the Warrior Princess)
• Halle Berry (Catwoman)
• Drew Barrymore and Cameron Diaz (the 2000 version of Charlie's Angels)
• Daryl Hannah (Kill Bill)
• Scarlett Johansson (Black Widow)
• Margot Robbie (Suicide Squad)

Watch out for the baseball bat!

RadioShack's former CEO tells Canada's National Post newspaper the surprising story of what happened after he left the company in 2004: When it came, rather than being crestfallen, he felt liberated, and free to pursue an "itch" that he had always felt the need to scratch. So he applied to medical school at McMaster University in Hamilton, Ontario... "I don't miss being a CEO one bit," Levy says. "I enjoyed it immensely, when I was doing it. But do I enjoy what I am doing now? The answer is, immensely."

Brian Levy, MD, was talking about his unusual career path with a reporter, via a socially-distanced phone call, on an April afternoon after wrapping up an overnight shift in the Emergency Department at Brampton Civic Hospital, northwest of Toronto. Brampton Civic is among the busiest emergency departments in Canada. The former CEO initially fancied becoming a psychiatrist, given all his years managing people, but he realized early on in medical school that he was more of a generalist, not to mention a Type-A, adrenaline-junky.

"Emergency medicine is a perfect fit for my personality," he says.
The article notes Levy's department "is eerily quiet, preparing for an expected surge in COVID-19 cases" -- and that in his spare time he's still an electronics geek.

"I am just one of those people who was very fortunate, where things worked out, and where I could do not just do one thing I really enjoyed in life, but two."

An anonymous reader quotes a report from the BBC: Scientists say they may have discovered why stress makes hair turn white, and a potential way of stopping it happening without reaching for the dye. Researchers behind the study, published in Nature, from the Universities of Sao Paulo and Harvard, believed the effects were linked to melanocyte stem cells, which produce melanin and are responsible for hair and skin color. And while carrying out in experiments on mice, they stumbled across evidence this was the case.

Pain in mice triggered the release of adrenaline and cortisol, making their hearts beat faster and blood pressure rise, affecting the nervous system and causing acute stress. This process then sped up the depletion of stem cells that produced melanin in hair follicles. In another experiment, the researchers found they could block the changes by giving the mice an anti-hypertensive, which treats high blood pressure. And by comparing the genes of mice in pain with other mice, they could identify the protein involved in causing damage to stem cells from stress. When this protein -- cyclin-dependent kinase (CDK) -- was suppressed, the treatment also prevented a change in the color of their fur. This leaves the door open for scientists to help delay the onset of grey hair by targeting CDK with a drug.

Just days after Pepsi announced that it would advertise its products in space using a Russian startup, the company now says it will no longer pursue the plans, avoiding what likely would have resulted in significant public criticism. Slashdot reader schwit1 shares a report from SpaceNews: The publication Futurism reported April 13 that PepsiCo's Russian subsidiary was working with a startup there called StartRocket to advertise an energy drink called "Adrenaline Rush" using satellites. The company has proposed flying a set of small satellites in formation, reflecting sunlight with Mylar sails to create logos or other advertising messages visible from the ground after sunset and before sunrise.

PepsiCo's headquarters in the United States has shot down the idea. "We can confirm StartRocket performed an exploratory test for stratosphere advertisements using the Adrenaline GameChangers logo," a company spokesperson told SpaceNews April 15. "This was a one-time event; we have no further plans to test or commercially use this technology at this time." The company didn't elaborate on the "exploratory test for stratosphere advertisements," but it appears to refer to a high-altitude balloon test of the technology that StartRocket says on its website it planned to carry out in April in cooperation with Russia's Skolkovo Institute of Science and Technology, or Skoltech. "People have a visceral dislike of space-based advertising," adds schwit1.

A Russian company called StartRocket says it's going to launch a cluster of cubesats into space that will act as an "orbital billboard," projecting enormous advertisements into the night sky like artificial constellations. And its first client, it says, will be PepsiCo -- which will use the system to promote a "campaign against stereotypes and unjustified prejudices against gamers" on behalf of an energy drink called Adrenaline Rush, reports Futurism. From the report: Yeah, the project sounds like an elaborate prank. But Russian PepsiCo spokesperson Olga Mangova confirmed to Futurism that the collaboration is real. "We believe in StartRocket potential," she wrote in an email. "Orbital billboards are the revolution on the market of communications. That's why on behalf of Adrenaline Rush -- PepsiCo Russia energy non-alcoholic drink, which is brand innovator, and supports everything new, and non-standard -- we agreed on this partnership."

An anonymous reader quotes a report from Ars Technica: A new, longer-term study of video game play from the Max Planck Institute for Human Development and Germany's University Clinic Hamburg-Eppendorf recently published in Molecular Psychiatry found that adults showed "no significant changes" on a wide variety of behavioral measures after two straight months of daily violent game play. Most scientific studies on the effects of video game violence measure participants right after the completion of a gameplay session, when the adrenaline prompted by the on-screen action is likely still pumping. Researcher Simone Kuhn and her co-authors argue that "effects observed only for a few minutes after short sessions of video gaming are not representative of what society at large is actually interested in, namely how habitual violent video game play affects behavior on a more long-term basis." To correct for the "priming" effects inherent in these other studies, researchers had 90 adult participants play either Grand Theft Auto V or The Sims 3 for at least 30 minutes every day over eight weeks (a control group played no games during the testing period). The adults chosen, who ranged from 18 to 45 years old, reported little to no video game play in the previous six months and were screened for pre-existing psychological problems before the tests. Over 208 separate comparisons (52 tests; violent vs. non-violent and control groups; pre- vs. post- and two-months-later tests), only three subjects showed a statistically significant effect of the violent gameplay at a 95 percent confidence level. Pure chance would predict more than 10 of the 208 comparisons would be significant at that level, leading the researchers to conclude "that there were no detrimental effects of violent video game play."

An anonymous reader quotes a report from The Verge: Even after puffing on just one electronic cigarette with nicotine, healthy non-smokers were found to have a biological marker known to increase the risk of heart disease in tobacco users, according to a new study. The research, published in Journal of the American Heart Association, shows that nicotine is not harmless, as many people believe. It can affect a smoker's health in more than one way, and not just by triggering addiction. Another study, conducted by Middlekauff that was published earlier this year, showed that people who use e-cigs almost every day have biological markers known to increase the risk of heart disease in tobacco users. These included an increase in adrenaline levels in the heart, which can predispose smokers to bad heart rhythms, heart attacks, and sudden death, as well as increased oxidative stress, an imbalance in the body's ability to defend itself against the damaging action of free radicals. Oxidative stress can lead to changes in blood fats and lead to arteriosclerosis.

That study, however, didn't show what exactly was causing those changes. E-cigarettes can have different flavoring and solvents, as well as nicotine. So to identify the culprit, Middlekauff brought 33 healthy non-smokers and non-vapers into the lab. On three different days, one month apart, the participants were asked to puff on three different kinds of e-cigarettes for 30 minutes: one with nicotine, one without nicotine, and a sham e-cig that was empty. The researchers did blood tests and measured the subjects' heart rhythms, and found that the participants had high levels of adrenaline in their hearts after they smoked the e-cig with nicotine, but not after they puffed on the e-cigarette without nicotine or the empty e-cig.

Press2ToContinue writes: A German carpenter has invented a valve which he claims will revolutionize contraception, by allowing a man to turn the flow of sperm from his testicles on and off at the flick of a switch. It (the switch, of course) is nearly an inch long and weighs less than a tenth of an ounce. It is surgically implanted on the vas deferens, the tube that carries sperm from the testicles, in a half-hour operation, and controlled by a switch beneath the skin of the scrotum.

So far Bimek is the only man who has the switches implanted, one for each testicle. I wonder what other switches we will see implanted into humans in the future? I think I'd like a valve for adrenaline control.

Hugh Pickens DOT Com writes "Sheila M. Elred writes in Discovery Magazine that a recent study has found that people at risk of depression were much less vulnerable if they identified as religious. Brain MRIs revealed that religious participants had thicker brain cortices than those who weren't as religious. 'One of the worst killers of brain cells is stress,' says Dr. Majid Fotuhi. 'Stress causes high levels of cortisol, and cortisol is toxic to the hippocampus. One way to reduce stress is through prayer. When you're praying and in the zone you feel a peace of mind and tranquility.' The reports concluded that a thicker cortex associated with a high importance of religion or spirituality may confer resilience to the development of depressive illness in individuals at high familial risk for major depression. The social element of attending religious services has also been linked to healthy brains. 'There's something magical about socializing,' says Fotuhi. 'It releases endorphins in the brain. It's hard to know whether it's through religion or a gathering of friends, but it improves brain health in the long term.'" (Read more, below.)

theodp writes: "Apple has recently disclosed a pending patent for Inferring User Mood Based on User and Group Characteristic Data, which has received surprisingly scant attention from the press even though it ups the ante for privacy intrusion. The brainchild of iAd team members, Apple boasts its invention will make it possible to 'charge a higher rate for mood based content delivery' by scrutinizing 'channel characteristics, demographic characteristics, behavioral characteristics, spatial-temporal characteristics, and mood-associated characteristics.' Apple further explains: 'Mood-associated physical characteristics can include heart rate; blood pressure; adrenaline level; perspiration rate; body temperature; vocal expression, e.g. voice level, voice pattern, voice stress, etc.; movement characteristics; facial expression; etc. Mood-associated behavioral characteristics can include sequence of content consumed, e.g. sequence of applications launched, rate at which the user changed applications, etc.; social networking activities, e.g. likes and/or comments on social media; user interface (UI) actions, e.g. rate of clicking, pressure applied to a touch screen, etc.; and/or emotional response to previously served targeted content. Mood-associated spatial-temporal characteristics can include location, date, day, time, and/or day part. The mood-associated characteristics can also include data regarding consumed content, such as music genre, application category, ESRB and/or MPAA rating, consumption time of day, consumption location, subject matter of the content, etc. In some cases, a user terminal can be equipped with hardware and/or software that facilitates the collection of mood-associated characteristic data. For example, a user terminal can include a sensor for detecting a user's heart rate or blood pressure. In another example, a user terminal can include a camera and software that performs facial recognition to detect a user's facial expressions.' Your move, Google!"

Last week you had the chance to ask software designer and international man on the run John McAfee about his exploits in business, programming, and the jungle. Mr. McAfee provided some extraordinarily entertaining and frank answers to your questions. Read below and enjoy.

SchrodingerZ writes "Two Americans have won the 2012 Nobel prize in Chemistry for their work in cell research. Their work involves the discovery and manipulation of the G-protein-coupled receptors, which detect signals outside the of cells they inhabit. 'The human body has about 1,000 kinds of such receptors, which enable it to respond to a wide variety of chemical signals, like adrenaline. Some receptors are in the nose, tongue and eyes, and let us sense smells, tastes and vision.' The winners are Robert J. Lefkowitz and Brian K. Kobilka. Lefkowitz works at the Howard Hughes Medical Institute and is a professor at Duke University Medical Center in Durham, North Carolina. Kobilka is a professor at Stanford University School of Medicine in California. Their research has helped create newer and more effective drugs with fewer side effects. More on G Protein-coupled Receptor research can be found in the Journal of Biological Chemistry."

Thelasko writes "Ever wonder why heads of statetend to age twice as fast as the rest of us? New research shows that adrenaline may damage DNA, potentially accelerating aging."

theodp writes "Working calmly in broad daylight and filming their efforts for YouTube posterity, a fake construction crew attached a large Microsoft Windows logo to the black facade of a soon-to-open Hamburg Apple Store. Neat hack in the MIT vein, but next time the crew might want to take along a pic of the Windows logo — with the adrenaline flowing, some of the colors got rearranged and were hung upside down."

An anonymous reader writes "A combination of factors like console penetration, piracy, and the huge inherent variability in PC hardware setups have made the PC a third-class citizen for many gaming genres, especially the kind of high-adrenaline action games that were once the PC's bread and butter. Epic is a company that has been vocal in its shift toward consoles, with many controversial statements dropped over the years in reference to piracy being the reason. So it was with some surprise that we noted Epic's VP, Mark Rein, pointing out recently that the PC is as important as ever. Why the turnaround? This article suggests that the extended length of the current console generation will drive some developers back to the PC as new games push up against hardware limits."

bowman9991 writes "Remember to check your palm to ensure that your crystal hasn't gone black. If it has, you better start running. The 1976 science fiction classic Logan's Run, starring Michael York, is being remade in 3-D with British writer Alex Garland now onboard to write the screenplay. Garland's film Sunshine, directed by Danny Boyle, was one of the stand-out science fiction films of the last decade, and he wrote the screenplays for Leonardo DiCaprio's The Beach (based on Garland's own novel) and the science fiction horror 28 Days Later (a massive adrenaline rush of a movie). This should give first-time director Carl Rinsch some great material to work with — a great premise meets a great writer."