Chrome Will Soon Have Its Own Dedicated Certificate Root Store (zdnet.com) 56
SpaceX Will 'Make Its Own Laws On Mars' (independent.co.uk) 293
"For services provided on Mars, or in transit to Mars via Starship or other colonization spacecraft, the parties recognize Mars as a free planet and that no Earth-based government has authority or sovereignty over Martian activities," the governing law section states. "Accordingly, disputes will be settled through self-governing principles, established in good faith, at the time of Martian settlement." Space systems engineer Erwan Beauvois said SpaceX's position was reminiscent of a declaration put forward by the Earthlight Foundation, a non-profit organization committed to preparing for the expansion of humanity beyond Earth. The Declaration of the Rights and Responsibilities of Humanity in the Universe states that space should be "considered free, by all, for all and to all."
Folding@Home Exascale Supercomputer Finds Potential Targets For COVID-19 Cure (networkworld.com) 38
And it did so. In a newly published paper, the Folding@home team said it was able to simulate an "unprecedented" 0.1 seconds of the viral proteome. They captured dramatic opening of the spike complex, as well as shape-shifting in other proteins that revealed more than 50 "cryptic" pockets that expand targeting options for the design of antivirals. [...] The model derived from the F@h simulations shows that the spike opens up and exposes buried surfaces. These surfaces are necessary for infecting a human cell and can also be targeted with antibodies or antivirals that bind to the surface to neutralize the virus and prevent it from infecting someone. "And the tech sector played a big role in helping the find," adds the anonymous Slashdot reader. "Microsoft, Nvidia, AMD, Intel, AWS, Oracle, and Cisco all helped with hardware and cloud services. Pure Storage donated a one petabyte all-flash storage array. Linus Tech Tips, a hobbyist YouTube channel for home system builders with 12 million followers, set up a 100TB server to take the load off."
Submission + - Folding@Home users find 50 potential drug targets in Covid virus (networkworld.com)
In its SARS-CoV-2 simulations, F@h first targeted the spike, the cone-shaped appendages on the surface of the virus consisting of three proteins. The spike must open to attach itself to a human cell to infiltrate and replicate. F@h's mission was to simulate this opening process to gain unique insight into what the open state looks like and find a way to inhibit the connection between the spike and human cells.
In a newly published paper, the Folding@home team said it was able to simulate an "unprecedented" 0.1 seconds of the viral proteome. They captured dramatic opening of the spike complex, as well as shape-shifting in other proteins that revealed more than 50 "cryptic" pockets that expand targeting options for the design of antivirals.
And the tech sector played a big role in helping the find.
Microsoft, Nvidia, AMD, Intel, AWS, Oracle, and Cisco all helped with hardware and cloud services. Pure Storage donated a one petabyte all-flash storage array. Linus Tech Tips, a hobbyist YouTube channel for home system builders with 12 million followers, set up a 100TB server to take the load off.
"We're extremely grateful for all the help," Bowman said. "The massive outpouring of support from citizen scientists and the help from the tech industry opened up scientific opportunities we wouldn't have had otherwise."
Researchers Discover Second 'Key' Used By Coronavirus To Enter Human Cells (helsinki.fi) 41
The discovery is important as it helps explain the rapid spread of the virus, and also helps define a potential target for antirviral intervention... The study itself was published in the Science magazine on the 20th of October.
More details announced by the University of Helsinki: "That SARS-CoV-2 uses the receptor ACE2 to infect our cells was known, but viruses often use multiple factors to maximize their infectious potential" says Dr. Giuseppe Balistreri, head of the research group Viral Cell Biology at the University of Helsinki involved in the study. "Unlike the main receptor ACE2, which is present in low levels, Neuropilin-1 is very abundant in the cells of the nasal cavity. This is a strategically important localization possibly contributing to the efficient infectivity of this new coronavirus, which has caused a major pandemic, spreading rapidly around the world", Balistreri explains...
By specifically blocking neuropilin-1 with antibodies, the researchers were able to significantly reduce infection in laboratory cell cultures. "If you think of ACE2 as a door lock to enter the cell, then neuropilin-1 could be a factor that directs the virus to the door. ACE2 is expressed at very low levels in most cells. Thus, it is not easy for the virus to find doors to enter. Other factors such as neuropilin-1 might help the virus finding its door", says Balistreri...
Balistreri cautiously concludes "it is currently too early to speculate whether blocking directly neuropilin could be a viable therapeutic approach, as this could lead to side effects. This will have to be looked at in future studies. Currently our laboratory is testing the effect of new molecules that we have specifically designed to interrupt the connection between the virus and neuropilin. Preliminary results are very promising and we hope to obtain validations in vivo in the near future."
Submission + - Second 'key' used by the SARS-CoV-2 virus to enter into human cells discovered 2
“That SARS-CoV-2 uses the receptor ACE2 to infect our cells was known, but viruses often use multiple factors to maximize their infectious potential” says Dr. Giuseppe Balistreri, head of the research group Viral Cell Biology at the University of Helsinki involved in the study. “Unlike the main receptor ACE2, which is present in low levels, Neuropilin-1 is very abundant in the cells of the nasal cavity. This is a strategically important localization possibly contributing to the efficient infectivity of this new coronavirus, which has caused a major pandemic, spreading rapidly around the world”, Balistreri explains. — -
By specifically blocking neuropilin-1 with antibodies, the researchers were able to significantly reduce infection in laboratory cell cultures. “If you think of ACE2 as a door lock to enter the cell, then neuropilin-1 could be a factor that directs the virus to the door. ACE2 is expressed at very low levels in most cells. Thus, it is not easy for the virus to find doors to enter. Other factors such as neuropilin-1 might help the virus finding its door”, says Balistreri. — -
Balistreri cautiously concludes “it is currently too early to speculate whether blocking directly neuropilin could be a viable therapeutic approach, as this could lead to side effects. This will have to be looked at in future studies. Currently our laboratory is testing the effect of new molecules that we have specifically designed to interrupt the connection between the virus and neuropilin. Preliminary results are very promising and we hope to obtain validations in vivo in the near future.”
The study itself was published in the Science magazine on the 20th of October.
'Hands-On With Amazon's Luna Game Streaming Service' (theverge.com) 47
The best performance (of course) came from a PC with a wired Ethernet connection and controller, with no other family members streaming video in the house. Playing Bloodstained: Ritual of the Night on that solid of a connection was virtually indistinguishable from the game running natively. (Switching back and forth, you can tell it takes oh-so-slightly longer to swing a sword, but it felt perfectly playable.) Admittedly, there are few benefits to actually using Luna to stream the game on a capable PC. On the other hand, Metro: Exodus, one of the most graphically intensive games available to stream, looked and played decidedly worse streamed to a web browser than it does on a capable gaming PC. Honestly, it doesn't look great in either Luna or Stadia, but at least Stadia could keep up with a mouse and keyboard. Luna's mouse was extremely laggy.
Using wireless connections introduces a lot more variables into Luna's performance. If you have a steady, strong Wi-Fi connection, Luna works pretty well, with little to no lag, smooth HD video, and responsive enough gameplay to enjoy even fast-paced platformers like Sonic Mania on an iPhone with a paired Bluetooth controller. But when Luna has a bad connection, it's rough. For some reason, Amazon doesn't seem to degrade the quality of video streaming when connection speeds are bad; it just tries to power on through by dropping frames until speeds pick up. I also ran into issues where audio started to lag behind what was otherwise smooth gameplay, presumably due to a sluggish connection. Right now, it seems that Luna's performance is almost entirely dependent on having good internet. Further reading: iOS Web App, Game Library, and App Functionality
GM To Invest More Than $2 Billion In US Manufacturing To Increase Electric Vehicle Production (cnbc.com) 67
The $2.2 billion in new investments will occur in the coming years, according to the company. Roughly $2 billion of that money will go toward a plant in Spring Hill, Tennessee, for production of future electric vehicles, including the recently unveiled Cadillac Lyriq crossover. Renovation work at the facility, which will be GM's third in the U.S. to produce EVs, will begin immediately, according to the automaker.
In connection with the announcement, GM will eventually move production of the GMC Acadia from the Tennessee plant to a facility in mid-Michigan. The company said it will invest more than $100 million at the Lansing Delta Township plant for assembly of the next-generation Acadia crossover at an undisclosed time. Separately from EVs, GM on Tuesday also announced new investments of roughly $53.3 million at four plants in Michigan to increase production of its heavy-duty pickup trucks, self-driving Cruise AV test vehicles and 10-speed transmissions.
Apple Fibs About iPhone 12 Pricing To Promote Wireless Carriers (sixcolors.com) 101
Backdoor In Kids' Smartwatch Makes It Possible For Someone To Covertly Take Pictures, Record Audio (theregister.com) 16
The researchers suggest these smartwatches could be used to capture photos covertly from its built-in camera, to track the wearer's location, and to conduct wiretapping via the built-in mic. They have not claimed any such surveillance has actually been done. The watches are marketed as a child's first phone, we're told, and thus contain a SIM card for connectivity (with an associated phone number). Parents can track the whereabouts of their offspring by using an app that finds the wearer of the watch. Xplora contends the security issue is just unused code from a prototype and has now been patched. But the company's smartwatches were among those cited by Mnemonic and Norwegian Consumer Council in 2017 for assorted security and privacy concerns.
With the appropriate Android intent, an incoming encrypted SMS message received by the Qihoo SMS app could be directed through the command dispatcher in the Persistent Connection Service to trigger an application command, like a remote memory snapshot. Exploiting this backdoor requires knowing the phone number of the target device and its factory-set encryption key. This data is available to those to Qihoo and Xplora, according to the researchers, and can be pulled off the device physically using specialist tools. This basically means ordinary folks aren't going to be hacked, either by the manufacturer under orders from Beijing or opportunistic miscreants attacking gizmos in the wild, though it is an issue for persons of interest. It also highlights the kind of code left lingering in mass-market devices.
Comcast Working Toward 10Gbps To Your Home Using Cable (zdnet.com) 136
According to a study by Dr. Raul Katz of Telecom Advisory Services, 10Gbps internet will generate at least $330 billion in total economic output and create more than 676,000 new jobs over the next seven years. It will do by enabling not just 8K video streams for everyone living in your home, but by enabling 5G access points, virtual reality applications, and telehealth. It's not just hardware that's making this possible. Comcast is a major open-source developer and user. As Comcast notes, "The trial was made possible not by a single technological innovation, but rather by a series of interrelated technologies that Comcast continues to test and deploy in its network, all powered by a DAA ecosystem. These include our increasingly virtualized, cloud-based network model." Comcast is working on the "10G" initiative along with NCTA, CableLabs, and SCTE, and other telecom and cable operators from around the world. In addition, Comcast and Charter Communications have worked closely to align on their approaches to 10Gbps and are driving technology standards and architectures to benefit everyone.
PS5 Teardown Video Confirms Faster Wi-Fi and USB Ports Than Xbox Series X (gamesradar.com) 56
As for the USB ports, we already knew that PS5 has a USB-C port and a USB-A port on the front. The teardown video confirms the type-C port will support 10Gbps transfer speeds, and it confirms that the two USB-A ports on the back will as well. The type-A port on the front isn't as quick, so if you plan to plug in an external PS5 SSD make sure you use one of the ports on the back. Xbox Series X doesn't include any type-C ports, and all of its type-A ports run at the standard 5gbps speed. If you know that fast connection speeds will make a big difference to your play experience, you may want to lean toward PS5 -- but as always, the biggest deciding factor should be what games you want to play and how well each console plays them. The Verge also notes the PS5 includes removable sides, dust catchers, and storage expansion.
Amazon Brings Eero Mesh Wi-Fi To ISPs (zdnet.com) 28
For ISPs, Eero Insight builds on Eero's existing Remote Network Management software. This combines monitoring user history to predict and address customer problems before they change from annoyances to real problems. It also includes network monitoring tools such as a network topology viewer, historical speed tests and bandwidth usage, RF diagnostics, alerts, audit logs, outage detection, fleet analysis, and network health. For users, all this should mean a more reliable internet connection and that's always good news.
Many Top AI Researchers Get Financial Backing From Big Tech (wired.com) 10
The Abdallas examined the CVs of 135 computer science faculty who work on AI at the four schools, looking for indications that the researcher had received funding from one or more tech companies. For 52 of those, they couldn't make a determination. Of the remaining 83 faculty, they found that 48, or 58 percent, had received funding such as a grant or a fellowship from one of 14 large technology companies: Alphabet, Amazon, Facebook, Microsoft, Apple, Nvidia, Intel, IBM, Huawei, Samsung, Uber, Alibaba, Element AI, or OpenAI. Among a smaller group of faculty that works on AI ethics, they also found that 58 percent of those had been funded by Big Tech. When any source of funding was included, including dual appointments, internships, and sabbaticals, 32 out of 33, or 97 percent, had financial ties to tech companies. "There are very few people that don't have some sort of connection to Big Tech," Abdalla says.
AT&T Finally Stops Selling DSL (usatoday.com) 148
DSL — a broadband connection delivered over old copper telephone lines — is no prize at AT&T. The company doesn't sell downloads faster than 6 Mbps, less than a fourth of the 25-Mbps minimum definition of the Federal Communications Commission and further cramps their utility with stringent data caps of just 150 gigabytes. But the technology that provided many people (myself included) their first real broadband still works to provide an always-on connection and far more capacity than satellite connectivity.
"I'm really not surprised that AT&T is phasing out DSL, as it's an obsolete technology," emailed one soon-be-stranded DSL subscriber, retiree Jack Mangold of Collettsville, North Carolina. "I am, however, very disappointed that AT&T has no interest in replacing DSL in rural areas with some other technology." AT&T reported 653,000 total DSL connections at the end of its second quarter, compared to 14.48 million on its fiber-optic and hybrid-fiber services. The latter, sold as "AT&T Internet," combines fiber trunk lines with DSL last-mile connections for faster speeds.
The company has seen DSL subscribers steadily dwindle. Bruce Leichtman, president and principal analyst at the research firm Leichtman Research Group, wrote in an email that two years ago, AT&T had just over a million DSL customers. "AT&T basically gave up on fighting cable over a third of its territory" said Dave Burstein, editor of the trade publication Fast Net News.
Could Our Entire Reality Be Part of a Simulation Created by Some Other Beings? (gizmodo.com.au) 203
In a recent article in Gizmodo, he answers the ultimate question: Could our entire reality be part of a simulation created by some other beings? Let's assume these extraterrestrial beings have a computer on which our universe is being "simulated". Simulated worlds are pretend worlds — a bit like the worlds on Minecraft or Fortnite, which are both simulations created by us. If we think about it like this, it also helps to suppose these "beings" are similar to us. They'd have to at least understand us to be able to simulate us. By narrowing the question down, we're now asking: is it possible we're living in a computer simulation run by beings like us? University of Oxford professor Nick Bostrom has thought a lot about this exact question. And he argues the answer is "yes". Not only does Bostrom think it's possible, he thinks there's a decent probability it's true...
According to Bostrom, if these simulated people (who are so much like us) don't realise they're in a simulation, then it's possible you and I are too. Suppose I guess we're not in a simulation and you guess we are. Who guessed best? Let's say there is just one "real" past. But these futuristic beings are also running many simulations of the past — different versions they made up. They could be running any number of simulations (it doesn't change the point Bostrom is trying to make) — but let's go with 200,000. Our guessing-game then is a bit like rolling a die with 200,000 sides. When I guess we are not simulated, I'm betting the die will be a specific number (let's make it 2), because there can only be one possible reality in which we're not simulated.
This means in every other scenario we are simulated, which is what you guessed. That's like betting the die will roll anything other than 2. So your bet is a far better one.
Professor Baron notes there's also two factors that decrease the likelihood of this hypothesis:
- How likely is it there are beings so advanced they can run simulations with people who are "conscious" like us in the first place?
- How likely is it such beings would run simulations even if they could? Maybe they have no interest in doing this.
"Sadly, we don't have enough evidence to help us decide."
Gizmodo doesn't indicate that professor Baron's came from a 9-year-old (as part of a series called "Curious Kids".) The 9-year-old's original wording of the question:
"Is it possible the whole observable universe is just a thing kept in a container, in a room where there are some other extraterrestrial beings much bigger than us?"
Graphical Linux Apps Are Coming to Windows Subsystem for Linux (zdnet.com) 89
It's always been possible to run Linux graphical programs such as the GIMP graphics editor, Evolution e-mail client, and LibreOffice on WSL. But it wasn't easy. You had to install a third-party X Window display server, such as the VcXsrv Windows X Server in Windows 10, and then do some tuning with both Windows and Linux to get them to work together smoothly. The X Window System underlies almost all Linux graphical user interfaces. Now, Microsoft has ported a Wayland display server to WSL. Wayland is the most popular X Window compatible server. In WSL2, it connects the graphical Linux applications via a Remote Desktop Protocol (RDP) connection to the main Windows display. This means you can run Linux and Windows GUI applications simultaneously on the same desktop screen....
Craig Loewen, Microsoft WSL Program Manager, added in a Twitter thread that the key differences between using a third-party X server and the built-in Wayland server is that: "You don't need to start up or start the server, we'll handle that for you." In addition, it comes with "Lovely integration with Windows," such as drop shadows and Linux icon support. Loewen also said you can run a Linux web browser in it. "We haven't tested it extensively with a full desktop environment yet, as we want to focus on running often asked for apps first, and primarily IDEs [integrated development environment] so you can run those in a full Linux environment," he said.
Don't get too excited about it just yet, though. Loewen continued, "We don't yet have an ETA for the beta channel, however, this work will be available in general for Insiders to try within the next couple of months."
Washington Emergency Responders First To Use SpaceX's Starlink Internet In the Field: 'It's Amazing' (cnbc.com) 85
Hall, whose division has used other satellite broadband services, said "there's really no comparison" between Starlink and traditional networks, where the satellites are farther away from the Earth in Geosynchronous or medium earth orbits. "Starlink easily doubles the bandwidth" in comparison, Hall said, noting that he's seen more than 150% decreases in latency. "I've seen lower than 30 millisecond latency consistently," he said. Hall said that, with other traditional services, it typically takes between 30 minutes to an hour to set up a satellite connection, "with a lot less speed and bandwidth and a lot higher latency in a much larger package."
By comparison, Hall emphasized that it took him between five and 10 minutes to set up and connect a Starlink terminal. And a single person can set up one of the devices: "It doesn't require a truck and a trailer and a whole lot of other additional equipment," Hall said. "I have spent the better part of four or five hours with some satellite equipment trying to get a good [connection]. So, to me, it's amazing," Hall added.
Microsoft's New Xbox App Will Let You Stream Xbox One Games To Your iPhone (theverge.com) 16
You will be able to access an Xbox console over Wi-Fi, or even an LTE or 5G connection, too. As this app takes control of your home Xbox, you can remotely start your console outside of your home. The Xbox will start up without a sound or the Xbox light at the front, and when you disconnect, it goes back into standby after a brief period of inactivity. A new Xbox app arrived on Android recently, and this updated iPhone version includes the same new design and new features.