Can't believe nobody has mentioned Indivo yet. http://indivohealth.org/
"Indivo is the original personally controlled health record (PCHR) system. A PCHR enables an individual to own and manage a complete, secure, digital copy of her health and wellness information. Indivo integrates health information across sites of care and over time. Indivo is free and open-source, uses open, unencumbered standards, and is actively deployed in diverse settings, in particular our own Children's Hospital Boston and the Dossia Consortium."
Mod parent up. I also work for a non-evil email marketing company, and the opt-out link DEFINITELY works. You can opt out of commercial email, and not all commercial email is spam.
I can't speak for anyone else, but I stopped running my own mail server when free webmail services got as fast, convenient, and effective at blocking spam. There's no real benefit to running my own server that outweighs the administration effort at this point.
Marketing Linux has always been a tricky proposition. As a community, we have relied on corporations who have a stake in the Linux operating system to market Linux to the world at large. Today, we have an opportunity to change that, and make Linux marketing as much a community effort as Linux development. That effort begins with the Tux 500 project. Our goal is simple: we want to collect community donations to enter a Linux sponsored car in the 2007 Indianapolis 500. We need your help! If less than 1% of the Linux community donates $1, this will happen... will you do your part?