"After all, Boeing has not been able to put something together against the mighty A380."
Boeing's not trying to put something up against the A380. It consciously decided to go another route with the 787 - offering airlines more smaller, cheaper jets that could fly into more airport than one huge megaplane limited to a few major hubs.
I'm not sure the industry has fully decided which model it prefers, but sales for the A380 have been sluggish:
While the 787's have been more in line with expectations before design.