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Comment: Re:Because Bureaucracy, stupid. (Score 1) 242

by pepty (#49144393) Attached to: The Peculiar Economics of Developing New Antibiotics
You are aiming at the wrong target. It's not some sort of zero sum game where spending more on physician samples or TV ads means spending less on R&D. Each dollar spent on ads more than pays for itself in extra revenue. And the system doesn't put HR, advertisers, and sales people above R&D - their jobs are all just as short lived these days in pharma. If you are going to blame anyone blame the investors - every free dollar goes to stock buybacks, not advertising. Anyway, I don't really see the congress and the senate directing the NIH on which drug candidates to pursue and which congressional districts to spend the money in working much more efficiently.

Comment: Re:i always thought this was a good idea (Score 1) 242

by pepty (#49133703) Attached to: The Peculiar Economics of Developing New Antibiotics

what really caught my attention was the plot of introduction and bacterial resistance over time. the newest antibiotics produced had a "shelf-life" of an order of magnitude less than their predecessors.

Some of that is because most new antibiotics aren't really all that new. The one on that list with the shortest "shelf life", levofloxacin, is a fluoroquinolone. We had already been using fluoroquinolones for 25 years by the time lefofloxacin came around.

Comment: Re:i always thought this was a good idea (Score 1) 242

by pepty (#49133665) Attached to: The Peculiar Economics of Developing New Antibiotics

Part of the problem is start up costs. To do serious research you need labs, equipment, researchers, staff, test subjects, etc. If you have that much money the bounty had better be huge so that you do not just decide to play the stock market or real estate instead.

And that is why biotech is funded by VC firms and eccentric rich folks.

Comment: Re:Because Bureaucracy, stupid. (Score 1) 242

by pepty (#49133615) Attached to: The Peculiar Economics of Developing New Antibiotics

If you look at any of the well-known names in the great advances in the science of medicine, rarely will you see a for-profit corporation listed.

But if you look at the big advances from over the past 30 years. PCR? Corporate. Cure for hepatitis? Corporate. Advances in DNA sequencing? Corporate.

Comment: Re:Because capitalism, idiots. (Score 2) 242

by pepty (#49133521) Attached to: The Peculiar Economics of Developing New Antibiotics

things got privatized, subsidies got cut down because government spending had to be cut down because of ...

The subsidies didn't get cut (well, maybe for a year or so during the last recession), they even increased faster than inflation most years. They just haven't grown nearly as fast as the cost of research. The concept of "low hanging fruit" applies big time to drug discovery, and the fruit that are left are much harder (and more expensive) to pick than the ones people chased in the 70's and the 80's. That said, year in, year out, about 25% of new drugs are invented in academia, principally through public funding. They are then licensed out to Pharma for the expensive part: clinical trials.

Comment: Re:Surely they meant (Score 1) 87

by pepty (#49124787) Attached to: Can Tracking Employees Improve Business?
Untracked freemen? The most valuable use of tracking will be of c-suite executives. At $1k per hour and up, their time is far too valuable to leave unexamined. And seeing as they are getting so much of their work done while out of the office (on the golf course, over drinks, etc) it would really be best if they were just tracked all the time.

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