IAABP (I am a biology professor).

For basic maths or physics, I agree with you that open source textbooks would be a great idea. The problem is when you talk about textbooks for more rapidly evolving fields, such as the life sciences. I can see how open source textbooks would be a very difficult proposition for biology texts. If the government wanted to fund such an endeavor it would not be "write once then forget about it", you would have to constantly update and revise it every few years. This means that there would need to be a permanent editorial board with support staff. The editorial board would have to have sufficient expertise in the field(s) to recognize what constitutes a significant advance in biology, as well as be able to decide what is an appropriate level of knowledge to present in textbook format. What with my teaching schedule and research demands, I just don't see me or anyone else in my field doing this, because it would be a full time endeavor that would take me out of the loop of my other professional duties. Unless there is a permanent position created for this (e.g., an NSF directorate with program officers and associated staff), I just don't see anyone risking their career for this.

A completely open and crowd-sourced book in the vein of Wikibooks is also doomed from the get-go, because any dolt can come along and edit things that have been carefully considered and written by an expert in the field (this is why I no longer contribute to Wikipedia). I suppose a hybrid model is possible, wherein edits may be submitted to a transparent editorial board for consideration, but again there is the issue of who would be willing to act as editor?

I suppose a third possibility to hold down costs is the formation of a non-profit publishing corporation that would publish works just as traditional publishing houses would, except that with a non-profit charter it would be able to keep prices low.

Most students who take an anatomy class at the level that requires animal dissection fall into two categories: those who are interested in an allied health profession (e.g., nursing, physical therapy) and those who are either interested in becoming professional biologists or medical doctors. I think you could make a pretty good case that in both cases, real dissections are an essential part of the students' training. Your average college student is not masochistic enough to take what is typically a course much tougher than a garden variety general education class. I don't know how the education system works in India, but I think the vast majority of biology departments in the US would not be willing to use models exclusive of real dissection. That being said, we do use models to supplement instruction, but these are physical models, not computer-based. Unless 3D displays become radically better and give tactile feedback, I don't see computer dissecting simulations displacing physical models either.

my new iPhone 4S out of the box had a fast draining battery. After messing with it in a completely non-scientific and non-systematic way and switching off some services (e.g., Ping) battery life is "normal" now. So it probably is a software issue.

my 10 year old LOVES Portal, and Portal 2 Co-op mode is loads of fun. It's not quite an adventure game in the pure sense, but the last level of Portal really captured her imagination, especially with the escape into the hidden areas of Aperture Labs. Portal 2 Co-op mode on an XBox is really good, because it's split screen, which makes it very easy to help out when the other player gets stuck.

I find it interesting that NASA showed no love for 2001: A Space Odyssey.

You, sir, are an idiot. Let's say someone exploits this and blows up a flight somewhere. Or, they manage to hijack the plane and fly it into some building (the how is irrelevant). I don't see any of the people killed by the collateral damage opting out of getting killed.

Phosphorus (or more precisely, phosphate) is used to form the covalent linkages between nucleotide bases in DNA and RNA. You could, in theory, retain the Watson-Crick basepairing of G, A, T, and C while replacing phosphate with something else such as arsenic. That is to say, the nucleotide bases are the bits of information, whereas the phosphate just holds it all together. To use a computer analogy, data is data, whether you store it on a hard drive or a flash drive.

What intrigues me more, is what about ATP? Adenosine triphosphate is not only used for making RNA, but it's also the universal common energy currency for almost all enzymes in all known organisms that catalyze endothermic reactions. If phosphate is not used in this arsenic-based organism, do they still use ATP as an energy source, and if not, what does it use and what kinds of adaptations does it enzymes have to accomodate this?

That mRNAs are edited post-transcriptionally has been known for some time now. In mammals, RNA modifying enzymes will act on specific mRNAs to alter their base structures, thereby changing their amino acid encoding. (too tired right now to provide a link, but this happens for mRNAs coding for AMPA-class glutamate-gated ion channels). It's not so much that it happens per se that is amazing; its that it happens at this large scale.

Much of this stuff is based on nex-gen high throughput sequencing technology, which has emerged just in the past 3-4 years or so. Very cool stuff.

why would I want to buy books and music that is tied to either a particular hardware platform and/or DRM scheme, at or above (or even near) cost of the physical media? Whenever possible I buy CDs or dead tree edition books. Occasionally I have bought DRM-free tracks from Amazon (I don't want to buy iTunes tracks because even though you can get DRM-free stuff from there it's inconvenient to move things between different devices), but overall I prefer physical media, which I can chose to sell later in the second-hand market if I so choose.

Its the same deal with e-textbooks. I teach university-level biology, and when the publisher is asking $100 for the e-book and $120 for the hardcopy, how can I recommend the ebook in good faith, especially when the publisher even outsources their DRM technology?