In rural Illinois you'd pay $500/month mortgage on a reasonable 3 bedroom home in a safe middle class neighborhood, in Dallas you'd pay maybe $700, in Albuquerque you'd pay $800, in Miami you'd pay $1200. So, the biggest gap there is $700/mo. That's $8,400 a year.
I paid around $1300 / month to rent a 2 bedroom apartment roughly 30 miles east of Manhattan. Was a decent but not great neighborhood. And this was 10 years ago. Mortgage + taxes for a decent sized house in NYC suburbs can easily run you over $3k / month. Now your biggest gap is $2500 / month, or over $30k a year. Other expenses add up as well. I've often joked that the nice thing about being a tourist from the NYC area is you barely notice how much you're getting gouged for food at tourist traps. It's a comparatively small markup.