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Comment: Re:Estrogen? (Score 1) 109

by inflamed (#47286907) Attached to: Scientists Successfully Grow Full Head of Hair On Bald Man

The chemical layout of Tofacitinib looks fairly similar to estrogen. We've known for ages that giving MPB-afflicted men estrogen will result in hair regrowth. Unfortunately, it also makes them grow breasts, but that's besides the point.

Throwing my moderations in this disccusion to reply to this - there ought to be a "Wrong" mod option ;) Nope, it's nothing like estrogen. One might as well conclude the structures are related to LSD: http://en.wikipedia.org/wiki/T... http://en.wikipedia.org/wiki/L... http://en.wikipedia.org/wiki/E... I am an organic chemist currently working in drug design and would conclude these compounds are, from a molecular standpoint, extremely disparate.

Comment: Re:Trust networks can fix this (Score 1) 120

by inflamed (#47185023) Attached to: Whom Must You Trust?

God this sounds familiar..... and that's because I wrote a PhD thesis about building a system to do something a lot like this. It involved a fairly mediocre web interface wrapping a database of trust relationships specified by end users. A trusts B for 0.7 and B trusts C for 0.6 then you can put together a trust level between A and C by multiplying those together with some user-tweakable distance dropoff. Those trust levels were then measured against the levels required for access to shared data. Maybe you would allow anyone with a 0.7 or higher to read a given document and a 0.9 or higher to contribute to it. It was an interesting idea, but man did I get tired of it by the end. If for some bizarre reason anyone wants to read bits of it google books has some indexed and I probably have a pdf laying around somewhere....

I figured it could be quite useful, but I was so fed up with the work in mid-2007 that I never looked back at it.

Thanks for laboring through a thesis on the topic, it's an occasional daydream of mine and I would love a copy. :-)

Comment: Re:Trust networks can fix this (Score 1) 120

by inflamed (#47185017) Attached to: Whom Must You Trust?

Which would work well if you could trust people to consistently submit "trust statements" truthfully and accurately. Sometimes people lie when they tell you who they trust and who they don't.

People lie but no so much when their lies are detremental to them. Such a web of trust could only be conned by 'fake' nodes which would have a very hard time developing any links to 'real' nodes.

Comment: Re:How is Burying Africa Under PCs Going to Help? (Score 1) 201

by inflamed (#46970797) Attached to: $7 USB Stick Aims To Bring Thousands of Poor People Online

Right. Most people in Africa have no electricity. Gotcha. And those without electricity are the ones paying for used PCs, $15k per container, to dump them to save Americans recycling dollars. Gotcha. The urban electrification rate in Africa is 59%. Nigeria had 6.9 million households with televisions in 2006. You are more likely to be hit by a Mercedes than to die from a machete or burning computer. This e-waste hoax never stops giving.

I don't know what your intent is in that statement but you forgot to mention that the distribution of Africa's population is 2:3 urban:rural, so the overall electrification rate is 24%. If your intent was to highlight that Africa has far bigger needs (and needs coverage of more pressing issues than) live USB thumb drives, you should have mentioned that.

Comment: Re: We're Not (Score 1) 634

by inflamed (#46966907) Attached to: Why Scientists Are Still Using FORTRAN in 2014

In your own domain -- Molecular Dynamics -- you might wish to send your initial configuration (position and velocities) to a colleague/reviewer who is using a different compiler. He could, in principle, reproduce your trajectory exactly. (Otherwise, there is a compiler error.)

You might not wish to routinely run with IEEE arithmetic, because it is slower. But for those folks who need it, it is right there at their fingertips and totally and completely (ANSI/ISO) standard.

The position and velocities or seed value will allow for reproduction of trajectories up to a certain point. Accumulation-derived errors take quite some time to develop and are acceptable. This is why relatively lossy GPU hybrid single-precision / double precision accumulation codes for CUDA are acceptable (and a game changer). Over an extended time the simulation will sample the same phase space. If the same phase space isn't sampled the simulation isn't run long enough or the model is bunk :-)

Comment: Re:It starts in the DNA (Score 1) 489

by inflamed (#45935547) Attached to: Tech's Gender and Race Gap Starts In High School

Genders, races, and social classes have different genetic makeups and hence different abilities.

It's taboo to say this. You should ask yourself why.

It's widely accepted that there are fewer genetic similiarities between individuals of the same 'race' as there are between individuals from different 'races.' There is tremendous overlap in most behavioural characteristics and physical abilities between male and female genders - most distributions appear bi-modal but in many cases 40+ % of the population falls on the side of the distribution attributed to the 'other' gender. You you refer to as taboo is taboo because it's wrong.

Comment: Re:Actually it starts at conception (Score 1) 489

by inflamed (#45934827) Attached to: Tech's Gender and Race Gap Starts In High School

I see your point but really, drop the "womyn-born-womyn" thing, it's...weird to read. I assume you must be transgendered? (which is totally fine by me, it's not like you got a choice) . In that case I get why you say it, but really, women since birth are still the norm, it's off to make the distinction in this context.

Making the distinction is a way of drawing attention to the norm of describing trans-gendered people as trans-gendered rather than as the gender they choose to identify with. Maybe a bit passive agressive, but hardly unwarranted.

Comment: Re:On the bright side (Score 1) 514

by inflamed (#45904511) Attached to: Weapons Systems That Kill According To Algorithms Are Coming. What To Do?

On the bright side, algorithm-driven machines are unlikely to pull their guns just because they have an attitude problem like some cops do.

No, an algorithm won't have an attitute problem. It might be selected by a human with a so-called algorithm problem, though. Feel safer?

You can bring any calculator you like to the midterm, as long as it doesn't dim the lights when you turn it on. -- Hepler, Systems Design 182

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