Here is the dietary composition. Sorry about the formatting. Table 1. Comparison of diets Normal (chow) High-fat High-sucrose PicoLab Rodent Diet kcal/kg diet 4070 4500 4000 Percent of kcal provided by: Protein 24.7 17.3 17.7 Carbohydrate 62.1 42.7 70.4 Fat 13.2 42.0 11.8 Sucrose, g/kg diet 31.8 341.46 645.6
He mostly just said that are mice are designed to run on a grain based diet. The study is clearly motivated by the natural diet of a particular organism. From the intro: "The Western diet contributes to many chronic, diet-related illnesses in the United States, including the obesity epidemic (Cordain et al., 2005). Western diets are typically high in fat and simple carbohydrates (CHOs) (Cordain et al., 2005). Higher intake of fats and refined sugars are associated with deficits in cognitive flexibility and hippocampal-dependent memory in humans (Kalmijn, 2000 and Francis and Stevenson, 2011) and an increase in the incidence of Alzheimer’s disease (Pasinetti, 2002)." When that diet is altered, things will change, including gut bacteria. Will there be other important changes? The study doesn't address that, but the sensible working hypothesis should be: yes, radical dietary changes affect more than gut bacteria. Let's look at the end of the discussion to see if this makes a difference: " Interestingly, mice fed 33% fat, in the form of lean ground beef, showed better long- and short-term memory than those on 12% fat (Li et al., 2009)." Maybe all the stuff in the diet besides the current macronutrients of interest actually matter??
If you're going to study high fat vs high carb, you'd at least control for protein and calories, right? NO!!!!!! THE HIGH FAT DIET HAS LESS PROTEIN AND MORE CALORIES!!!!! Previous studies in this field have also been misleading: "It’s well known that in mice, “high-fat diets” induce endotoxemia. But these diets aren’t necessarily high in fat – any pelleted rodent food in which fat provides more than 20% of calories may be called “high-fat.” The critical difference of “high-fat diets” from chow is that they are composed of purified nutrients – starch, sugar, oil, vitamins, and minerals – whereas chow is composed of natural whole foods such as wheat, corn, and seeds." (http://perfecthealthdiet.com/2015/06/disease-begins-in-the-mucus/) At least they didn't use a "high fat high cholesterol" diet with ridiculous amounts of purified cholesterol.
Take it back, insensitive clod. 7 digits is not a lobotomy.
You could probably even figure out the sum of all paths by using a geometric series.
But are these answers valid if the ring of points lies on a discontinuous surface, of if the surface is unwalkable?
If an engineer doesn’t know why he should be building something, then that something should be avoided. If he can’t explain why he designed a bridge in a particular way, then stay off the bridge! If his boss can’t explain why a bridge would improve traffic patterns, in some quantitative way, then it shouldn’t be built either. When these conditions are violated, it’s usually for the benefit of someone besides the engineers. A well trained engineer would not build a bridge to nowhere, or allow an unsafe shuttle to fly. These decisions are made by people who answer to social and personal pressures but not science or engineering principles. Part of the problem is greed, but another part is ignorance. Both will be big problems with AI, and studying humanities will not allow anyone to intelligently decide whether a particular machine resembling AI should or should not be built. They have no standing under which to make an argument. You can’t simply expect them to spew out some philosophy and convince a legal body that they understand the consequences of the machine better than those who designed it, and can quantify its purpose and abilities. You can’t effectively regulate what you don’t understand, and you won’t understand anything resembling AI in any meaningful way without some technical background. The precautionary principle is your only regulatory hope, and realistically that isn’t going to prevent AI malfeasance. Since we don’t know what this AI will look like, the answers to which technoligies should be suppressed must be picked up as its designers and observers go along. A solid background in science can’t just be picked up as you go along, if you’ve ignored it your whole life. But with a good background in some scientific area, other scientific expertise can be readily picked up along the way. I have no background in chemistry but now I work in a lab where biochemistry is a main focus. I’m picking it up to research level, but that would not be possible with a pure education in humanities. And the implications of any technoligy I may create? How could I expect someone to understand those implications without understanding the technology?
If critical thinking involves "knowing" when to apply equations, then critical thinkers must have experience applying equations. That comes from STEM education and not humanities. Understanding people and their motivations is surely important for selling stuff, and many other things. Fortunately there are (arguably) sciences that deal with these subjects directly - psychology and sociology.
And then you have to change it every three months. And not to anything you've used in the last decade.
That's to make you appreciate all the hard work involved in keeping with the diet - counting calories, reducing caloric intake month after month, huddling with a nutritionist, extra exercise and lots of yoga. Also there is stigma involved - some people have a very negative view of crossfit, and hate paleo by association. Some people just think that only an idiot would remove entire classes of food from their diet. Vegans avoid paleo because it involves eating animals or animal products.
Still, Hell no. It's fairly new and expensive, so every lab in the world is not going to have one. But it's commonplace enough that if it's used to support a result, it's not necessarily even advertised in the abstract. These results are cited by other labs as inspiration and support for their work, which in my view counts as usage. Moreover, its usage and acceptance has grown much faster than, say, the confocal microscope.
My altered state of consciousness is a superposition of worlds where Sagan is both right and wrong.
Veracity is not a property of an academic journal. It can refer to a statement. For an example of a statement lacking veracity, consider the assertion that 'does not produce fatal overdoses' is an adverse effect of cannabis.
The number from your rectal studies institute is probably more correct. The total number of people that have been imprisoned is likely much less than the number currently in prison.
Here are a few high-profile citations from the last year. Super-resolution microscopy on fixed cells is a big deal. That's not an argument against its worth. A technology need not satisfy all your wishes to be extraordinarily worthwhile. Current practices on a commercial system do not necessarily limit what is possible in a research setting. http://www.ncbi.nlm.nih.gov/pu... http://www.ncbi.nlm.nih.gov/pu... http://www.ncbi.nlm.nih.gov/pu... http://www.ncbi.nlm.nih.gov/pu... http://www.ncbi.nlm.nih.gov/pu... http://www.ncbi.nlm.nih.gov/pu...