How do you colonize low earth orbit or the Lagrange points?
Park an ion drive or solar sail on a near Earth asteroid, move it into a convenient orbit, and mine it for colony materials.
In fact, a race of space-faring tardigrades from a low-gravity moon sounds like a good start for a novel.
Maybe they could require registration for commercially purchased drones. But what stops me from building a drone in my garage and zipping it around the neighborhood?