Comment You are not up to date (Score 2) 22
The synthetic yeast genome project (the precursor to this project) is more or less complete (currently at about 70%). Most chromosomes of Saccharomyces cerevisiae have been successfully synthesized from scratch. We are not speaking of a few hundred nucleotides (that was state of the art a couple of decades ago), but millions, all properly wrapped up in the proteins stabilizing chromosomes in eukaryotic cells. This project is a logical extension.