The biggest problem with CIGS as a production material is probably that it can't "piggyback" on the industry built up for the computer industry. I know that sounds strange, since its lack of reliance on that source of material is also its advantage, but tools to work with CIGS have to be developed more or less from scratch. That's expensive, and the reason that these initial investments are important. The process must be bootstrapped.
I would argue, however, that this is actually partly an advantage. The semiconductor industry is based on batch processes for the most part. That usually means slow. Miasole's factory uses reel-to-reel manufacturing, and will be able to exploit the high volume equipment designed for this type of manufacturing.