Japan, Australia, the UK and other countries with sane gun laws have murders, but almost no mass killings. The reason for this is the lack of firearms, whether you like to admit it or not, the abundance of guns is directly correlated with a high number of shootings. This is true for a lot of countries where guns are abundant (whether they're legal or not).
I know you said "almost," but still feel obligated to link to this. Don't need guns for a mass killing.
In modern history, we're known to do things with uranium and lead that we shouldn't have.
If you want to see a synaptic-effect drug that is a real advance, look at sugammadex for reversal of aminosteroid paralytics.
It'd be a lot easier to take a look at Sugammadex if it ever got FDA approval...
If the business can't generate enough cash flow to pay the liability insurance bill, maybe the business shouldn't exist.
But if they can just go a couple of states over and not have to pay, they'd be crazy to stay.
The two most common things in the Universe are hydrogen and stupidity. -- Harlan Ellison