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Motherboard: ASUS Z9PA-U8 - $277.99
64GB 16x4 (4 slots still free) - $720
Power supply 1500 Watt - $374
Video cards: ??? not currently available
Apple with similar specs: $7,899
So that leaves $2,723 for video cards, I can't find any suggested prices on the D500 or D700, except that Apple charges $300 per card to upgrade from D500 to D700.
Of course if you wanted 12 cores you could save a bundle and just get a dual socket board and 2 6 core cpus. Also the MB supports a lot more ram etc, but is a lot bigger.
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Yeah, someone should invent "echo madvise >
Except that crappy workaround doesn't fix it, you have to set it to never as a workaround or simply disable transparent huge pages on boot.