I wish they would focus on shifting ads away from the current "be as annoying and in your face as possible" trend, and over to more non-intrusive forms of ads. I'm sure the reason ads have become so obnoxious is that it leads to more clicks, but that so many now choose to block them might be a good indication it's time to reevaluate.
My adblocker accepts non-intrusive ads by default. Get your ads on that whitelist and the problem is solved. Personally, I don't care about a static image or text box. I do care about blinking pop-overs with audio. Whenever I get a "we see you are running an ad-blocker, would you mind telling us why?" questionnaire from a website, I tell them the same thing.