Yeah, I think that variety is definitely the solution to a lot of RSI problems. Different people have different shaped bodies, and required different keyboards, mice, chairs, and other office equipment.
I personally find old fashioned, non-split keyboards much more comfortable, even though I spend a considerable amount of time typing on a keyboard. I also have my keyboard situated quite far into my desk. My keyboard is situated so that my entire forearm rests on the desk when typing. This changes all the generally understood "rules" for typing.
First rule is that you shouldn't rest your arms, and your hands shouldn't be resting on the table, but elevated. This is a problem for people that keep the keyboard close to them because it usually means their wrists are on the corner of the desk, cutting off circulation. When you rest you entire forearm on the desk, there isn't a whole lot of pressure in one spot, and your wrists actually stay elevated anyway.
The second "rule" is that you should use a split keyboard. With my keyboard so far from the edge of my desk, my arms and wrists are actually in a straight line. If I tried to have the keyboard closer to me, then sure, my wrists would be contorted sideways causing problems.