Almost all of the software I have worked on commercially has been successful, and none of it has been open source (I have worked on open source projects, just not as a job). However, I also have a manager who is a developer with an MBA (he was a developer, and he got the MBA while developing) and a project manager who knows technology. Even the requested upgrades to the legacy systems we have get done on schedule and on budget

Kennestone Hospital in Marietta, GA (a suburb of Atlanta) has one to. They also do radio ads as well for various forms of cancer, as well as a big banner in front of the hospital) http://cancer.wellstar.org/content.aspx?id=38605&section=cyberknife

I work for a rich media vendor (basically, middle men between ad agencies and website publishers for rich media advertisements), and we reduce our impact on page load time by using fast edge servers via a content delivery network to serve our JavaScript file, whether on the page or on the ad server's iframe, and then not load content until after the page is finished loading. Seems to work pretty well, as we recieve very few complaints from most of our publishers (including Yahoo!, MSN, AOL, and even Slashdot itself)