Well, part of the reason it is all there (and other ISM bands like 915 MHz and 5.8 GHz) is because the stuff *can* work with interference. This property is useful both when dealing with other "intentional radiators" and with industrial emissions, so it makes sense to put them in the same area. Pretty much the FCC and other regulatory agencies put an (almost) free-for-all sign up and said "if you can make it work, go for it, just don't complain if it doesn't work at all."
However, you wouldn't be able to use the ISM bands -- or, quite frankly, any frequency close to them -- for weak-signal work like satellite. It would be like trying to whisper at Woodstock.