nor shall any person
If I am giving testimony as to another's guilt or innocence and the defense asks me a direct question (to cast doubt to either my honesty, or if I have an issue with the defendant, for example) that would have me admitting to my own criminal behavior (connected or not to this case) or committing perjury, I may refuse to answer this question.
In this case I am providing "third-party" testimony and am covered by both the intent and the letter of the Fifth Amendment.
As a note, in many countries this protection is also included in civil cases, not just criminal ones.
"I don't believe in sweeping social change being manifested by one person, unless he has an atomic weapon." -- Howard Chaykin