I think the whole question is a misunderstanding of analysis, caused by the idiotic Mars ONE bullshit/hype.
Besides the exception of some kind of emergency mission to save the planet like in the Hollywood film Armageddon, there really is no reason so send anyone on a suicide mission.
It's a waste of resources to send a 'suicide mission'....space is the most expensive thing humans do...
Also, If we have the ability to travel to another planet, we have the ability to return or begin permanent colonization.
All "risk" is a question of engineering.
The Mars ONE hype has brought focus on things, one of which is why is space the most expensive thing that humans do. Its expensive because of the assumption that you have to engineer for every possibility imaginable. If you reduce the possibilities then the engineering simplifies and the cost reduces.
Its not necessarily a 'suicide mission' just a mission that would not involve a planned return to Earth. If such a mission has quantifiable aims and those are met wouldn't that stop it being a waste of resources, depending on the cost you place on a non-returning astronaut?
There have been many endeavours over history that people have undertaken knowing that there was little, or no, prospect of return. What is different about this being in space?