Comment Self Bootstrapping Death Ray (Score 4, Interesting) 272
Directly providing the power to vaporize a person is not the elegant way to do it. The correct, elegant mad scientist method is to use the power contained in the vaporized mass to power the vaporization.
Consider if you develop a means to "program" a plasma such that it generates a contracting magnetic field that causes fusion inside the vaporizing object and then absorbs some of the energy from this fusion reaction to power itself.
Now you're talking! Now you've got an effect that can vaporize any object provided you can provide the initial energy requirement.
There could be variants on this. Perhaps you've got an effect that flips matter into antimatter and absorbs some of the released energy to continue the effect.
If this is an expanding effect instead of a collapsing effect you've got a world killer like the weapons in Ender's Game.