This is the problem exactly. I can deal with odd formatting from a PG book (though as you say, most are fine); what pisses me off is recent, full price ebooks where there has obviously not been the slightest attempt at editing or typesetting. One I got recently had a consistent problem where quoted text changed font & size after the first paragraph, which is pretty jarring. A full price book on my Nook should be a better experience than PG or scanned & OCR'd pdb were on my old Palm Pilot but sometimes these types of glitches just take you out of the experience & actually seem worse.
The Oatmeal's book "5 Very Good Reasons to Punch a Dolphin in the Mouth" I luckily got out of the library (through Overdrive) - the images are so small as to be unreadable, both on the PC & ipad. If you look at the Play store, there are lots of good reviews, but they're all from Goodreads & such for the paper version. I'm sure it's funny, if you can read it; if I'd paid money for this pile of bits I'd be pissed. Does the publisher not own an ipad or a Kindle Fire? Did they not load it on one single device & say to themselves, "hmm, this really sucks, let's fix it"?