I just posted this an hour ago: http://www.youtube.com/user/41D57#p/a/u/0/c5cF8Us4cK4

While the video pokes fun at size and boot time, for the average desktop user, those things remain largely the same.

We use these: http://www.wiebetech.com/products/cases.php

It's like having a proper hard-case for each disk, and although it won't protect them from a fall it makes it easy to line them all up on a bookshelf or in a rack/drawer system and pull them out when needed.

We also read each drive at least once every 6 months to ensure the drive can re-new any weak magnetic sectors/blocks.