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Biotech

Submission + - New and Improved Deadly Snail Venom

SoyChemist writes: In 2004, the FDA approved the cone snail venom ziconotide (Prialt) for the treatment of chronic pain. It is only used for severe cases because it must be injected directly into the spinal column. This month, researchers from the University of Utah have reported the discovery of a new snail venom with a completely different amino acid sequence. Because it very selectively attaches to and blocks nerve signals by binding to a particular type of acetylcholine receptor without causing any collateral damage, the newly discovered venom could also become a fantastic medical tool.
Microsoft

Submission + - Vista problems reaching mainstream press

mcgrew (sm62704) writes: "The tech press has been talking about Vista's shortcomings for quite a while now; Slashdot has posted numerous stories. Today I saw a "Tech Talk" in the St Louis Post Dispatch, one of the US' largest mainstream newspapers. The article is about a "normal" (i.e., non-geek) user's woes. From the article:

After his initial computer purchase from a local retailer, he tried starting Vista and had no luck: It gagged on other preinstalled software, and the retailer had no remedy. He received a replacement laptop.

On our colleague's second try, he ran into a wall with Microsoft, which insisted through its online validation process that his copy of Vista was not legitimate. About a third of all new Vista owners with valid copies of the OS already have suffered through this. The retailer assured our colleague that his Vista was valid but replaced his laptop again anyway to solve the problem.

Armed with yet another new laptop, our colleague escaped repeats of the first two problems but hit a new bump: Vista refused to acknowledge his computer's peripheral devices, even though Microsoft's own hardware compatibility list said it should.

He returned to the retailer and this time asked for his money back. He says he might try buying his first Mac with the refund. "There's only so much I'm willing to put up with," our colleague said. "I just wanted the [expletive] computer to work, you know. Isn't that all anyone wants?"
I notice that he returned the second computer because of MS' onerous DRM, which insisted that the OS was counterfeit. I'm aghast that one in three valid copies are flagged as "pirated". Note: I'm not a Mac user; my OS of choice is Mandriva."
Slashdot.org

Submission + - Slashdot's Firehose: Misplaced democracy?

PetManimal writes: "The Slashdot Firehose is a 'bad metaphor and a bad idea,' or so says Computerworld's Joyce Carpenter, who has been using the user-directed submission rating system since it was introduced a few months ago. She points to an increase in unworthy submissions — some of which seem to be part of 'viral marketing scams' — and says that they make Firehose unpleasant for everyone:

The increased number of unworthy submissions makes more unpleasant work for the editors as well as members of the community. A bigger hose with more crap in it just means that the editors have to read all that crap — and so do the voting members of the community. That's just more work for everyone.
She also questions whether Zonk and Co. are even using the recommendations that make it to the top of the Firehose ratings:

So far as I can tell, the editors still make the decisions. Good for them. I have no need for democracy in the selection of stories at a site that has done an excellent, if elitist, job of using editorial judgment. That's what makes it such a good site. Drain the hydrant and throw away with the hose.
"
Patents

Submission + - Prizes vs. Patents: a Nobel laureate's perspective

benesch writes: "Joseph Stiglitz, recipient of the Nobel Prize in Economics, points out the flaws of our patent system "The fundamental problem with the patent system is simple: it is based on restricting the use of knowledge. Because there is no extra cost associated with an additional individual enjoying the benefits of any piece of knowledge, restricting knowledge is inefficient." He goes on to suggest prizes as a more efficient alternative "Of course, the patent system is itself a prize system, albeit a peculiar one: the prize is temporary monopoly power, implying high prices and restricted access to the benefits that can be derived from the new knowledge. By contrast, the type of prize system I have in mind would rely on competitive markets to lower prices and make the fruits of the knowledge available as widely as possible. With better-directed incentives (more research dollars spent on more important diseases, less money spent on wasteful and distorted marketing), we could have better health at lower cost.""
Patents

Submission + - No MPEG, WMA/V, DVD, Quicktime breaks Dell Linux

An anonymous reader writes: In Dells latest blog they state: "At this time, we are not including any support for proprietary audio or video codecs that are not already distributed with Ubuntu 7.04. These include MPEG 1/2/3/4, WMA, WMV, DVD, Quicktime, etc. We are evaluating options for providing this support in the future"

Ubuntu better make it exceptionally easy for Dell customers to install these codecs or Dell's Linux could be a mitigated failure.

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