Extensions only matter if we're talking about porting over NoScript.
I recently made an honest effort to try out the latest stable release of Opera. I was pleased to note that it had a lot of the features baked-in that I was adding to Chrome and Firefox. It was fast and seemed to do a good job as a web browser. However, the first time I visited some forums looking for solutions to a random problem, I was sorely disappointed with the lack of Noscript. Sure, the message boards usually say "Sure you can disable Javascript, do 'this' from the menu", but that isn't the kind of granularity that NoScript offers. Then, there's a substitute called "Blockit", which is apparently supposed to act like Noscript. However, the configuration screen is painful and the addon appeared to be broken; it didn't appear to give me a NoScript-like button to control each page. The plethora of annoying bits on the sites I visited researching how to get a working Noscript substitute in Opera encouraged me to drop Opera. What irony.
I've been spoiled by NoScript. I'm not particularly a Firefox fanboy--it has its own share of problems and issues--but it does run NoScript and I can't stand browsing the web without it.