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Comment Re:Huh? (Score 1) 191

"Yet beyond monetary damages, the case has zero bearing on the modern technology industry, as both the MP3 music file format and the iPod itself have waned in popularity"

Wait, what? People no longer use MP3s? They don't buy iPods?

They've also technically got it backwards. Neither Apple nor Real were distributing mp3s, but DRM'd music files in other formats - mp3s were never targeted by Apple's countermeasures to Real's hack. Today it's actually possible to get most music in plain mp3 format from Amazon and other online retailers so, if anything, mp3 is now vastly more popular than before (at least as a legitimate distribution format).

Comment Re:The Fix: Buy good Chocolate! (Score 2) 323

How much do you think a standard Hershey Bar (plain, 43g) should cost in $USD? Genuinely curious.

I'm no chocolate snob, but you couldn't pay me to eat that stuff. Who ever thought it would be a good idea to add sour milk to perfectly adequate chocolate? It tastes like they've mixed it with baby vomit. As an emergency measure, all cocoa intended for Hershey's production should be seized and used to establish a National Cocoa Reserve. Only manufacturers with a track record of selling an edible product (like Ghirardelli) would then be allowed to draw on it. Sound reasonable?

Comment Re:yet another duplication of what's out there (Score 1) 105

Here's what the pie is. The pie is a market. The pie is cuttable into unlimited slices. Who gets the pie, depends on if they get into the market. Getting into the market guarantees them a slice of the pie. This is why Google entered the market. Because of capitalism, gobbling up as much pie as possible is always desired, even if it's unnecessary and duplicates what's already out there a million times over.

I don't understand! Do you have a car analogy?

Also, does this mean no more free pie? Will google crack down on Youtube downloaders and ad blockers that already give naughty, naughty people most of the advantages of this service for free..?

Comment Re:Real article is here (Score 4, Interesting) 275

Rather an odd study. Viral DNA apparently present in nearly half the subjects. They went straight to a mouse model before attempting to confirm the (small) effect in a larger, independent human cohort. No evidence that the virus actually infects mammalian cells, which would be an extremely unusual host range (the only precedent of anything similar they could find to cite is in an obscure Ukrainian journal). I'd say 'more research is needed', but maybe that's just the virus talking.

Comment Re:This is safe? (Score 1) 198

And on that point, has anybody actually isolated and sequenced a confirmed ebola sample from a human subject who died from that specific infection in the affected region?

Yes, there are complete genomes from 78 cases (not necessarily fatal, but with confirmed EVD) in this publication alone:

http://www.ncbi.nlm.nih.gov/pu...

This genomic sequence cannot be detected in uninfected individuals. It simply isn't there. Run the analysis on a thousand random blood samples from, say, the US or Europe, and you'll never see it. Does that suggest anything to you? (I assume from your language, which is similar to that used by HIV denialists, that it might not!).

Comment Re:ebola doesn't have DNA - it has RNA (Score 4, Informative) 198

The vaccine vector is an Adenovirus, a DNA virus. The recombinant Ebola virus gene it carries will be in the form of DNA, designed to encode the same protein as the original RNA gene in the Ebola virus. It's the protein that is important, since this what the immune system will raise its response against.

Comment Re:This is safe? (Score 1) 198

Viruses are really damned small, and finding the right organism in an infected cell is anything but easy. Cells are full of all kinds of molecule-sized bits and pieces of shit. As of today, it is not even a certainty that the ebola virus has been positively identified, let alone properly categorized; there have been reports of over 250 mutation variants, any of which might be a mutated ebola virus, or maybe just another virus which might just have been present through the isolation process. Maybe just random bits of crap from a previous disease vector or vaccination injection. Nobody really knows for sure. It's pretty murky down there, and determining which organism causes what effects is a sloppy science, and it takes a huge amount of time and energy to even approximate answers.

Viruses are indeed really damned small, but not much else is true in this paragraph, which is mostly FUD. Nobody outside the ranks of medical conspiracy theorists doubts that the Ebola virus has been positively identified. We are about as certain of this are we are about the identity of, say, a tiger or an oak tree. Its genome has been completely sequenced many times. Yes, mutations have been found in viruses from the current epidemic that weren't found in previous outbreaks. There's nothing surprising about this - we see it every time the virus emerges from the animal reservoir and causes a new outbreak. There is no question of this being just some 'random crap' or anything to do with vaccinations. The mutations occur at specific positions within the well-defined sequence of the viral genome, and if you are so inclined you can go along to the UCSC genome website and see exactly where they are: http://genome.ucsc.edu/cgi-bin...

The specific viral genes selected for insertion into the (adenovirus) vaccine vector weren't chosen at random - the Ebola virus has been studied for decades and there is a great deal of data on the functions of the proteins that its genes encode. Of course we can't know for sure if a new type of vaccine is safe and effective until it is actually tested, but this is a long way from just having some sort of vague hunch that it might be OK, as you seem to be suggesting.

Comment Re:Classic shell (Score 1) 242

If you like living on the edge where any windows update can obliterate your copy of Windows and make the UI unusable.

Sounds like FUD. Classic Shell, occasionally updated, has been perfectly stable for me over the last 18 months or so of Windows updates. Install and configure Classic Start Menu (switching off all the charms and hot corner nonsense) and spend a few minutes setting file associations to not load any Metro apps, and you've got a perfectly decent version of Windows with some improvements over 7, like faster booting. The window decorations are a bit flat, but I never liked Aero Glass either. Windows 8 ought only to be a problem for inexperienced users who don't yet know how to deal with its annoyances, people stuck with locked down systems, and MS shareholders. Surely most people reading Slashdor don't fall into these categories?

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