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Medicine

Submission + - Drug company disguised advertising as science (nature.com)

ananyo writes: "A former pharmaceutical company employee has blown the whistle on drug promotion disguised as science.
Drug companies occasionally conduct post-marketing studies to collect data on the safety and efficacy of drugs in the real world, after they’ve been approved by the US Food and Drug Administration. “However,” writes the anonymous author in an editorial in the British Medical Journal (subscription), “some of the [post-marketing] studies I worked on were not designed to determine the overall risk:benefit balance of the drug in the general population. They were designed to support and disseminate a marketing message.”
According to the whistleblower, the results of these studies were often dubious. “We occasionally resorted to ‘playing’ with the data that had originally failed to show the expected result,” he says. “This was done by altering the statistical method until any statistical significance was found.” He adds that the company sometimes omitted negative results and played down harmful side effects.
Nature says it was unable to work out who the writer was but they likely worked on diabetes and the studies criticized were from the Denmark-based pharmaceutical company Novo Nordisk."

Comment Do they still work? (Score 2) 687

(As in; are they still effective marketing. Obviously, the fact that they do work and that it is unpleasant work is pretty much the entire point of OP.)

I like the sight of a beautiful woman as much as the next guy. Preferrably the sight of one who is comfortable and enjoying themselves. But thats entirely beside the point.

I would not buy a tech product from a company that thought so little of me that they thought that draping sexy women over their product would convince me to buy it, and thought so little of their own product that they thought that it needed sexy women nearby to distract from its technical details (read shortcomings.)

I guess this is why I don't do trade conferrences, and why they don't market to me, but it still surprises me that this works terribly well. I mean sure; us male geeks may be conditioned early-on to be suckers for a pretty girl, and even moreso if its one who can spout a line of technical specs, but we're talking hardware here - if you're not paying more attention to the specs than the girl spouting them, you aren't a real geek.

Comment Re:How? (Score 1) 324

Yeah, like I said; I have trouble with the statement; but until I get a chance to read the research, I'm giving it the benefit of the doubt. I can think of plausible mechanisms that would at least contribute to that effect, so while its difficult to believe that they would be of an appropriate magnitude, I'm not going to dismiss it out of hand.

My only real point was that the /. summary says one thing and the original article says the opposite... and then to show that again for this post, I went back and re-read the summary, discovered I'd misread it the first time, and got embarassed. So there's that.

Comment Re:How? (Score 1) 324

Well yes and no. There's the water in the reservoirs themselves, that is still missing from the oceans. That doesn't account for a continuing decrease in sea levels though, except for the continuous creation of new reservoirs. But reservoirs also have an enormous evaporation rate, and the water that we take out of them for use often never makes it back to the ocean, for various reasons: we spray it on our gardens and golf courses and it evaporates, is absorbed by plants, or returns direct to groundwater. We flush it down our toilets, and it goes to sewage treatment plants where it sits in enormous pools with high evaporation rates while being treated. In California it gets run in open-topped canals through deserts down the length of the state, evaporating all the way. That sort of thing. The water isn't removed from the ecosystem, but a fair bit of it bypasses the ocean part of the cycle. Even ignoring things like Hoover dam and the Colorado - which makes a bad example because of the huge amount of its water which gets used out of the river's watershed - you generally see much smaller amounts of water flowing out the ocean ends of rivers after they're dammed (for water storage; I'd imagine the effects of flood control dams are smaller, but I couldn't personally vouch for that.)

Having said all of that, its hard to imagine that any of it adds up to a hill of beans when it comes to _ocean_ levels. I'm more-or-less trusting the quoted research on that, not having the time to chase it up myself at the moment.

Comment Re:How? (Score 3, Informative) 324

I wondered this too... so I went and read the linked original article, which quite clearly states:

"Artificial reservoirs, such as the Hoover Dam on the Colorado River and the Three Gorges Dam on the Yangtze River in China, have the opposite effect, locking up water that would otherwise flow into the seas."

So your (and my) suspicions were correct; reservoirs don't make this problem worse, as the /. summary implies, but instead partially counteract it. Bad /. summary; no biscuit.

Comment Ask Slashdot: Would You Like to Be Unemployed? (Score 2) 403

What a strange place to ask this question... unless you're just looking for us to cooborate your already fixed opinion. Of course Slashdot thinks its a bad idea; this place is full of programmers who don't want to see their jobs outsourced. Might as well ask oil executives their opinons on solar energy and alternative fuels.

(Of course, someone will now contradict me by posting in favor of outsourcing. We're not just geeks; we're contrary Slashdot geeks...)

Comment Re:Public vs. Private posts? (Score 1) 456

Exactly.

Lets see, we have a service that lets you post your life on a billboard, and one that advertises that its like that other one, only lets you keep some privacy and only shout to your friends. And it turns out that the people who were enticed by that pitch to move to the second service with more privacy... wanted more privacy. Truly a stunning turn of events.

Tune in next week where we show that people who buy sports cars on average drive faster than people who drive subcompacts...

Comment Good Plan, but.. (Score 1) 101

They're going to need to be very careful on the implementation. Define "properly" peer-reviewed. Is the journal liable for libel (now there's a terrible turn of phrase) if it turns out the peer review wasn't "proper"? Can someone challenge the propriety of the peer review in court?

Don't get me wrong; sounds like a step in the right direction. I'd just hate to see it abused to discourage scientific publishing in England.

Submission + - Biggest Kickstarter Project Ever Surpasses $10 Million; Cuts Off Funding (techdirt.com)

TheGift73 writes: "We keep hearing that these new business models and platforms really can't handle "big" projects. While part of the charm and power of these platforms is that they can fund smaller "long tail" projects that might never otherwise see the light of day, there's no reason that they can't do bigger projects as well. A few weeks ago, we told you about the Kickstarter campaign for the Pebble e-watch, which was the fastest growing Kickstarter project ever, surpassing $1 million in just 28 hours, and hitting $4.5 million by the time we got our post out."

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