Comment Re:Fuck kidney (Score 1) 55
Structurally, the liver is not that complex, and -- as previously mentioned -- has amazing regenerative capacity.
Physiologically and biochemically, yes, individual hepatocytes have a phenomenal array of activities and functions. However, once you get hepatocytes developing in the liver scaffold, the fact that each of them is a marvel of biology is a moot point.
The liver's function is currently not something we can reproduce, but developing tech to regrow compatible livers en toto would solve the problem without having to address the 500+ functions you mention. I imagine it's progressing nicely.
The kidney is the opposite. We can artificially accomplish most of the function of a kidney (though it's horribly expensive an inconvenient), but the structure is a bit more complex than the liver (more varieties of specialized epithelium, for example, and the glomerulus is currently impossible to build) with very poor regenerative properties. Losing some liver usually means the organ grows some extra to replace the lost bit, losing some kidney generally does not.
Conveniently, by using scaffolding already built and seeding with cells that can differentiate into the appropriate types, we can sort of short-cut the necessity of trying to build either organ whole.
Go science!