A specialized use case, but I would like one for digital art. It would be required to be fairly powerful, run a full PC operating system, and have a built in digitizer. Also, I would expect it to work well in a laptop format with a convertible/detachable/wireless keyboard.
"How would you carry that around?"
Carrying around is easy, put it an a backpack or messenger bag, 15-17" laptops are not a new thing.
"How the hell would you hold it?"
I normally wouldn't. As a laptop it would be used as any other laptop. As a tablet it would primarily normally be used on my lap, or on a desk/table using a kickstand, portable stand, or less portable docking station depending on location.