Yes, smack in the middle of some of the highest price real estate in the country. Even coming from the peninsula, it will take you 30 min to get to the Caltrain station and park (longer if you want to make sure you can get parking), 1h for Caltrain, and probably another hour for the mismatch in schedules before you get on HSR.
There are planned HSR stations at San Francisco, San Jose, and two intermediate stops on the peninsula. Current timetables for CalTrain indicate that local service (a.k.a. stopping at every station) San Francisco to San Jose takes 90 minutes. One hour will get you from SF to Menlo Park. Getting from an arbitrary CalTrain station to an HSR station would likely take 30 minutes or less. You can cut that time dramatically by catching a limited or express CalTrain run, and likely this time will go down for all runs once the electrification of CalTrain is completed.
Let's not forget, either, that where HSR and CalTrain share tracks they would all have to be grade separated. This too will increase the speed and reliability of CalTrain. So, realistically, you're looking at regional improvements that benefit more than a few million people.
Likewise, if you're spending an hour looking for parking, you're doing it wrong. Using public transit, or door to door shuttle service would cut that time down.
You're being overly pessimistic, why? Because you'd prefer we subsidize the airlines? Please. Let's not forget that SFO is near capacity in good weather, but in any inclement weather the runways are structured such that you incur massive delays.
Then you need transportation at the other end, since you probably don't have business near the HSR terminal.
Again, HSR at the San Francisco end is stumbling distance from the financial center of the Bay Area, so, likely yes you do have business nearby.