Ideally, better laws will shut these parasites down. It took a century to stop factories from pouring toxic waste into rivers, and even longer to stop cities doing the same thing with untreated sewage.
On Sunday, I was heading toward NH to have lunch with my brother when I saw a dazed driver wandering out into Route 93 from his newly-smashed car. In a situation like that, nobody would complain about "wasting time" to lend a hand. The problem was clear, what I could do about it was clear, and the stakes were very high. If spam were like that I wouldn't whine about wasting my time to stop it. But as it is, I just delete the ads for Viagra and horny teen farmgirls, or hang up on the autodialer, or reply to "How are _you_ today?" with "Please put me on your don't-call-list."
Yes, I did get the guy off the road, eventually, but I was darn glad when the ambulance arrived to take over.