Comment Minor correction: CCR5 Delta 32 != Antibodies (Score 1) 263
CCR5 is not about antibodies. I'm one of the individuals with the homozygous (two copies) CCR5 Delta 32 mutation. It's a deletion mutation, meaning that I lack functional receptors HIV-1 binds to on the surface of my T-cells. My understanding is that except for theoretical strains of HIV that bind to the CXCR4 co-receptor, most of the strains prevalent in the wild will have no more effect on me than parvo virus.
That doesn't mean I get a free pass to be irresponsible, but it does mean that I stand a significantly reduced chance of contracting HIV through stupid behavior, that if smallpox ever breaks out I'll be really busy helping to heal the sick, that bubonic plague isn't too much of a problem for me either, but that West Nile can really screw me up.
That doesn't mean I get a free pass to be irresponsible, but it does mean that I stand a significantly reduced chance of contracting HIV through stupid behavior, that if smallpox ever breaks out I'll be really busy helping to heal the sick, that bubonic plague isn't too much of a problem for me either, but that West Nile can really screw me up.