Best Web-Based Medical Billing Software of 2026

RXNT's cloud-based, ambulatory healthcare software empowers medical practices and healthcare organizations of all sizes and most specialties to launch, succeed, and scale through innovative, data-backed, AI-powered software. Our integrated, ONC-certified healthcare software system—including Electronic Health Records, Practice Management, Medical Billing and RCM, E-Prescribing, Practice Scheduling, Patient Portal, and more—will streamline clinical outcomes, practice management, and revenue cycle management for your medical organization. RXNT is trusted by over 60 thousand providers and medical professionals across all 50 states in the U.S.A. to drive business growth, optimize operations, and improve the quality of patient care. All of our SaaS-based software products can be purchased standalone, but you can run you entire practice—from encounter to billing—with our unified Full Suite system. It utilizes a secure, central database so your data passes through every product in real-time from anywhere. Using our software, more than 125MM prescriptions have been transmitted and over $7B in claims have been processed. Our predictable, transparent subscription pricing model includes free setup & training, support, mobile apps, and more.

Service Center by Office Ally is trusted by more than 80,000 healthcare providers and health services organizations to help them take complete control of their revenue cycle. Service Center can verify patient eligibility and benefits, submit, correct, and check claims status online, and receive remittance advice. Accepting standard ANSI formats, data entry, and pipe-delimited formats, Service Center helps streamline administrative tasks and create more efficient workflows for providers.

AdvancedMD is the all-in-one cloud-based medical office software trusted by thousands of independent practices to run smarter, faster, and more profitably. It unifies practice management, EHR, and patient engagement into a single seamless platform — eliminating the inefficiencies of disconnected systems. The AI Clinical Assistant is at the core of the modern AdvancedMD experience. It powers ambient listening and auto-transcription, capturing patient conversations and turning them into structured chart documentation in moments — reducing note-writing from 15 minutes to seconds. AI-generated chart action items, pre-visit summaries, and insurance card capture further eliminate manual data entry, so your staff spends less time on paperwork and more time with patients. AI Narrative Insights continuously analyzes practice performance data, surfacing trends and opportunities you can act on directly from your dashboard. On the financial side, AdvancedMD strengthens your bottom line with robust revenue cycle management, a multi-clearinghouse model including a Waystar partnership for cleaner claims, and computer-assisted coding to maximize reimbursement. The result: faster payments, fewer denials, and healthier cash flow. Built on secure AWS infrastructure with Password Breach Detection, AdvancedMD keeps your practice protected and compliant — accessible from any device, anywhere, anytime. Whether you're a solo provider or a growing multi-specialty group, AdvancedMD scales with you — delivering an intelligent, unified experience that lets you focus on what matters most: your patients. The future of independent practice isn't just surviving — it's thriving. AdvancedMD gives you the technology to do both, without the complexity.

Billing and Practice Management: Facilitates claims handling, checks for eligibility, personalized billing dashboards, code and charge input, and provides analytical insights through more than 100 report options.

XpertCoding by XpertDox is an AI medical coding software that utilizes advanced artificial intelligence, machine learning, and natural language processing (NLP) to automatically code medical claims within 24 hours. This software streamlines and enhances the coding process, ensuring faster and more accurate claim submissions and maximizing financial returns for healthcare organizations. Features include a comprehensive coding audit trail, minimal need for human supervision, a clinical documentation improvement module, seamless integration with EHR systems, a business intelligence platform, a flexible cost structure, significant reduction in claim denials and coding costs, and risk-free implementation with no initial fee and a free first month. XpertCoding's automated coding software ensures timely payments for healthcare providers & organizations, accelerating the revenue cycle and allowing them to focus on patient care. Choose XpertCoding for reliable, efficient, and precise medical coding tailored to your practice.

Improve workflow processes, revenue optimization, business development and marketing, and improve clinical outcomes. You can connect your entire community seamlessly, empower your staff to work better, and get a holistic view on your community's financial performance. This will give you the proactive insights that you need to streamline operations and optimize revenue. You'll be able to centralize all your clinical and business operations on one platform, which will give you the simplified solutions, economies-of-scale and enhanced security that you need to be a top-quality care provider. You will have a better understanding of your performance in relation to your financial and occupancy goals, your staff's safety and satisfaction, and you will be able to tackle the many challenges that face you every day.

MedEvolve Practice Management (PM) software is an intuitive solution that helps to reduces write-offs, denials and reimbursement delays. MedEvolve PM has automated features that help improve billing and collections with as little manual work effort as possible. MedEvolve Practice Management (PM) software allows front desk staff to easily make appointment changes, handle scheduling complications and quickly resolve physician delays. With an automated waitlist, practices can quickly fill empty appointment slots, even after last-minute cancellations. The solution also has built-in analytics, so you will have a complete view of your practice’s financial and operational performance. Advanced real-time analytics make it easy to monitor Key Performance Indicators (KPIs) and benchmarks so you can compare against similar practice. MedEvolve PM integrates with over 40 different EHR systems. We believe physician practices should be able to choose the best EHR for their clinicians, and the best practice management software for their administrative and billing staff.

Mercury One Plus is an intermediate billing solution for Medical Practice Management that provides the fundamentals of Revenue Cycle Management. It acts as a stepping-stone from standard billing to intermediate billing. Mercury One Plus is only available on the cloud. It offers the highest level security and you can access it anywhere, 24/7. Mercury One Plus is a complete product with a lot of functionality. It includes patient demographics inputter, 100 plus reports to choose from, charge input, full history patient activity, ERA posting and credit card acceptance, among other things. Mercury Products are HIPAA-compliant and have a connection guaranteed to any clearinghouse or insurer. Mercury One Plus will help you tune up your system daily with its automated job system. This includes: housecleaning, folder maintenance, daily backups, 837 exports and 835 imports. All subscriptions include expert support from CrisSoft.

Over 25 years ago, one of our founders was working as the IT Director of a large behavioural health and residential services agency in New York. Sensing a need for a better way to track and report on their services, he developed a case management system for his agency. Over time, two other agencies joined in and helped expand the software so that it could serve the needs of virtually any human services agency in the country. Today, Foothold’s team and our software support hundreds of agencies across the nation, in Guam, and in Puerto Rico. With our technology expertise and roots in human services, we continue to empower agencies to focus on their missions.

Comp Pro Med assists labs of all sizes to improve their productivity and efficiency by providing the most flexible LIS available. Polytech LIS offers over 350 options to customize the software to meet your workflow and automation needs. Polytech LIS comes with a built-in generator that can generate unlimited reports to suit any need. Your lab will be up and running quickly with a dedicated support team. Polytech LIS was created by lab people, for lab people. Our system architecture is designed to ensure that your lab never experiences any downtime. The software is robust, comprehensive, and easy to use. 90% of lab work can be done on one screen. Comp Pro Med is the difference. A LIS that meets your needs today and into the future.

Insurance companies run AI to review, adjust, and deny claims. Most practices still work them by hand. Altair closes that gap: an AI-native, done-for-you medical billing service that runs your full revenue cycle, from eligibility and prior authorization to claims, denials, and appeals, backed by a US-based team of expert billers. This is a service that does the work, not software your staff operates. Your practice hires and manages no one. Altair scrubs every claim against payer edits and medical-necessity policies before it goes out, works denials to root cause, and files appeals. It learns how each payer behaves, so first-pass acceptance and net collection rate climb the longer you use it. Coding and charge capture stay with your practice; Altair runs everything else in the cycle. Altair also runs patient billing and collections on your behalf: it sends statements, sends payment reminders by text and email, sets up and manages payment plans, follows up on unpaid balances, and pursues aged patient accounts receivable, so the patient share is collected in full, not just invoiced. A live financial view shows what is billed, in flight, paid, and at risk, surfaces underpayments, and forecasts the cash to come, so you always know where your money is without waiting for a monthly report. Altair integrates with every EHR, practice management system, and clearinghouse on the market, with onboarding in hours. Independent practices, medical groups, and billing companies get the billing firepower of a large organization without hiring an army. Payers built their AI to pay you less. Altair gets you paid in full.

AZZLY Rize is the premier clinical and business platform for addiction treatment and mental health organizations. As a modern technology platform, AZZLY Rize is a system that can scale with you. Use as little or as many of the features and functions available based on your program and staff needs. Key features for OUTPATIENT Programs include e-check-in, scheduling, appointment reminder, Zoom telehealth, treatment plans, progress notes, assessments and surveys. For RESIDENTIAL Programs: census, medication management, bed board, withdrawal management, DrFirst e-prescribing, EPCS, PDMP and labs. For all Programs: alerts, patient engagement, 5 star implementation and support services, and seamless electronic billing and claims submission. As a true all-in-one platform, we empower treatment centers to take control of their compliance and revenue cycle management and reporting requirements. As a purpose-built tool for mental health and substance use disorder programs, we offer a flexible pricing plan to replace dated technology. Use our compliant Master Library of Forms or we configure your documentation forms to match what you use today. Hosted in Microsoft Azure Private Cloud Network for added security and HIPAA privacy.

Speedy Claims was the top CMS-1500 software by providing the best customer care to our thousands of clients across America. Medical billing is not something people are excited about. It is a tedious task that you must do. Although it won't be an enjoyable task, it doesn’t have to be difficult or time-consuming. Speedy Claims CMS-1500 software makes it easy to complete the job quickly and efficiently, allowing you more time for the things that you love, such as helping patients. It's the best HCFA 1500 software on the market, with a simple interface and powerful features to eliminate repetitive work. It has powerful error checking built in to ensure that your HCFA 1500 form fills out correctly and is complete. This prevents CMS-1500 claims being denied.

To ensure the well-being of both patients and providers, independent practices require comprehensive solutions. Each product offered by Tebra is specifically designed to enhance and streamline the entire patient-practice experience, and when integrated into a unified platform, it functions as a complete operating system that benefits both providers and patients. By utilizing this connected system, practices can effectively attract new patients while retaining existing ones through enhanced digital visibility. Furthermore, patients are empowered at every communication point, fostering a seamless experience that promotes trust and contributes to a healthier practice environment. A state-of-the-art, certified EHR solution tailored to meet the demands of today’s healthcare providers is also included, equipping practices with essential features such as advanced charting, efficient documentation processes, a holistic view of patient histories, electronic prescriptions, lab integrations, telehealth capabilities, and much more, enabling providers to maintain control over their care delivery methods. With these innovative tools at their disposal, practices can thrive in an increasingly competitive healthcare landscape.

It is time-consuming to manage your therapy and rehabilitation practice. You spend hours on paperwork and scheduling. Raintree's EMR can help you manage your practice more efficiently. Our all-in-one solution will give you the tools you need for a more efficient therapy and rehab practice. It will also help you improve patient care and allow you to do what you love. Our EMR solution for electronic medical records is the most complete and user-friendly on the market. Are you spending too much time manually managing billing and collections? These are the most important aspects of your rehab or therapy practice and you need a new solution. Raintree's RCM tools are proven to automate your entire operation. Raintree's proven RCM tools have helped clients save money on billing and collections. Learn more today.

OpenPM offers a fully integrated billing and claims management system that automates accounts receivables management while producing extensive reports to help you better manage your organization. As a browser-based application, OpenPM provides a level of access to your system never before possible. Our real-time claims management features will improve your cash flow and streamline billing and claims follow-up processes. We welcome you to explore OpenPM further and contact us for a customized demonstration for your practice. Medical billing software, revenue cycle management solutions, practice management software, practice management system, medical practice management, EMR integration, EHR integration, practice management scheduling, patient scheduling, online patient billing, patient billing, automatic patient billing and payments, patient payments, electronic patient payments

Effective collaboration in patient care hinges on continuous connectivity and access to the latest information. It has become increasingly crucial to streamline the exchange of this information with insurers. Availity simplifies the process of working with payers, guiding you from the initial verification of a patient's eligibility to the final resolution of reimbursements. Clinicians desire quick and straightforward access to health plan details. With Availity Essentials, a complimentary solution backed by health plans, providers can benefit from real-time data exchanges with numerous payers they frequently engage with. Additionally, Availity offers a premium option known as Availity Essentials Pro, which aims to improve revenue cycle performance, minimize claim denials, and secure patient payments more effectively. By relying on Availity as your trusted source for payer information, you can dedicate your attention to delivering quality patient care. Their electronic data interchange (EDI) clearinghouse and API solutions enable providers to seamlessly integrate HIPAA transactions along with other essential functionalities into their practice management systems, ultimately enhancing operational efficiency. This comprehensive approach ensures that healthcare providers can maintain focus on their primary mission: patient well-being.

Zanda, formerly Power Diary, is the online practice-management software that health practitioners trust around the world. It has a calendar, appointment reminders via SMS and email, customisable templates for treatment notes, client invoicing and payments, online bookings with 2-way SMS chat, Telehealth as well as an in-platform manual. It also integrates with Xero Mailchimp Stripe Physiotrack Medicare (AU) and many other systems. Zanda's clients include sole practitioners, large multi-location practices, and physiotherapists. They also include psychologists. Zanda provides a Money-Back Guarantee for a period of 12 months to make your decision easier. They offer excellent support and will import your data for free.

Audit Manager simplifies medical auditing by combining audit management, education, and reporting into a single web-based solution. Audit Manager was created by auditors for auditors. It allows you to audit on terms. You can access immediate reporting, customize templates, and have total control over your entire audit program. Audit Manager will increase your auditing efficiency up to 40%, reduce denials, and identify up to 10% missed revenue. Now included — Audit Manager features built-in Tableau integration to provide in-depth analytics and reporting.

NextGen Healthcare is a leader in healthcare software and services that enables the transformation of ambulatory health care. NextGen Office (1-10 doctors) and NextGen Enterprise (10+ doctors) are smart electronic health record solutions that help ambulatory practices reduce the burden of documentation, improve clinical outcomes, connect to other health systems, increase provider and patient satisfaction, streamline revenue cycles, and foster healthier communities.

OptiMantra is an established EMR and practice management platform focused on integrative and wellness practices. The platform is highly adaptable and robust - it includes online appointments, patient messaging and email reminders, a patient portal, intake forms and customizable charting, integrated payment processing, integrated labs and imaging, insurance billing, in-program tele-health, inventory management, and more. It's easy to get set-up! OptiMantra offers tailored onboarding support.

eMedicalPractice is a healthcare technology company based in Delray Beach, Florida. Since 2008, we have offered ambulatory practices and medical management groups an arsenal of fully integrated and highly customizable enterprise solutions including our Electronic Health Record (EHR), Practice Management, Telemedicine, Clearinghouse, Revenue Cycle Management, Billing, Patient Engagement and MIPS Registry platforms.

LIS 365, a laboratory information system (LIS), is a software system that records, manages and stores data for medical and clinical laboratories. The best LIS software is able to send laboratory test orders to instruments, track those orders and record the results. LIS Software should be used to automate workflows for the same reason it is used for record keeping. While it may not save time, it will save you valuable effort. LIS365 empowers laboratories to increase revenues and improve customer retention. We assist them in increasing efficiency, streamlining workflows, ensuring patient safety, and ensuring patient satisfaction. The following functions are common in a LIS (laboratory Information System): Sample Management, Workflow management and reporting.

No matter how big or small your company is, our software can help you manage and accelerate your performance. Our secure and scalable case management software can be adapted to meet your clients' needs and empower your agency. PlanStreet's compliance with HIPAA/HITRUST security standards ensures that sensitive data and files are protected. It is time to stop using manual forms and processes. Switch to PlanStreet to automate client engagements, cases, forms, and files. We are confident that PlanStreet can help you and your team plan, execute, track, and monitor work.

GreenSense Billing Medical Scheduling simplifies your life for all your medical scheduling needs. You won't have to worry about medical billing again. Insurance eligibility verification Find out about the patient's insurance coverage before they make an appointment. You can run individual queries as well as run a batch of queries using our eEligibility verification tool. Automated appointment reminders and alerts reduce delays and late arrivals. To avoid no-shows and late arrivals, notify your patients before each appointment. Snapshot of Your Medical Schedule. In the Instant view you can see all your medical appointments for each provider, and any specific practice location.