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Description
ESMFold2 builds upon its predecessor, ESMFold, by establishing a new benchmark in single-sequence structure prediction and facilitating the creation of novel functional proteins via exploration of the latent space within the ESMC model. This advanced model is capable of forecasting high-resolution, all-atom 3D structures of biomolecular complexes straight from the amino acid sequence, and it allows for the incorporation of multiple sequence alignments to improve accuracy on difficult targets. Tailored for predicting structures through both sequence and structure modalities, it employs ESM representations that drive a series of looped folding layers while a diffusion model translates pairwise representations into atomic-resolution outcomes. ESMFold2 excels in predicting protein structures from amino acid sequences, providing detailed structural data, including precise all-atom coordinates for both backbone and side chains, along with confidence metrics and optional distogram predictions for in-depth structural evaluation. Furthermore, its innovative approach enhances the understanding of protein folding dynamics and functional implications, making it a valuable tool for researchers in the field.
Description
SKY-001 is an innovative engineering world model introduced by Skyfall AI, designed to create structured visual design plans based on user prompts, reference images, and spatial parameters. It disassembles engineered entities into distinct assemblies and components, subsequently forecasting the sequences for sketches and 3D construction states related to each part. The capabilities of this model are showcased through computer-aided design (CAD) tasks, including the reconstruction of mechanical assemblies, as well as in building information modeling (BIM) tasks, which involve translating building outlines and specifications into detailed floor plans. Its hierarchical approach allows for parallel exploration of various design candidates, enhances the refinement of component geometries, and facilitates planning across numerous construction phases. Skyfall AI promotes SKY-001 as a research tool for applications in design and engineering, while also hinting at possible expansions into other areas of physical design. Those interested in utilizing this innovative tool can find a link to join a waitlist for future access on the product page, ensuring they remain updated on its public release. This model represents a significant step forward in the integration of artificial intelligence into practical design workflows.
API Access
Has API
Yes
API Access
Has API
No
Screenshots View All
No images available
Integrations
Biohub
No
Mira
No
Python
No
Pricing Details
Free
Free Trial
No
Free Version
Yes
Pricing Details
No price information available.
Free Trial
No
Free Version
No
Deployment
Web-Based
Yes
On-Premises
No
iPhone App
No
iPad App
No
Android App
No
Windows
No
Mac
No
Linux
No
Chromebook
No
Deployment
Web-Based
Yes
On-Premises
No
iPhone App
No
iPad App
No
Android App
No
Windows
No
Mac
No
Linux
No
Chromebook
No
Customer Support
Business Hours
No
Live Rep (24/7)
No
Online Support
Yes
Customer Support
Business Hours
No
Live Rep (24/7)
No
Online Support
No
Types of Training
Training Docs
Yes
Webinars
No
Live Training (Online)
No
In Person
No
Types of Training
Training Docs
No
Webinars
No
Live Training (Online)
No
In Person
No
Vendor Details
Company Name
Biohub
Founded
2016
Country
United States
Website
biohub.ai/models/esmfold2
Vendor Details
Company Name
Skyfall AI
Founded
2024
Country
United States
Website
skyfall.ai/sky-001