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Description

ESMFold2 builds upon its predecessor, ESMFold, by establishing a new benchmark in single-sequence structure prediction and facilitating the creation of novel functional proteins via exploration of the latent space within the ESMC model. This advanced model is capable of forecasting high-resolution, all-atom 3D structures of biomolecular complexes straight from the amino acid sequence, and it allows for the incorporation of multiple sequence alignments to improve accuracy on difficult targets. Tailored for predicting structures through both sequence and structure modalities, it employs ESM representations that drive a series of looped folding layers while a diffusion model translates pairwise representations into atomic-resolution outcomes. ESMFold2 excels in predicting protein structures from amino acid sequences, providing detailed structural data, including precise all-atom coordinates for both backbone and side chains, along with confidence metrics and optional distogram predictions for in-depth structural evaluation. Furthermore, its innovative approach enhances the understanding of protein folding dynamics and functional implications, making it a valuable tool for researchers in the field.

Description

SKY-001 is an innovative engineering world model introduced by Skyfall AI, designed to create structured visual design plans based on user prompts, reference images, and spatial parameters. It disassembles engineered entities into distinct assemblies and components, subsequently forecasting the sequences for sketches and 3D construction states related to each part. The capabilities of this model are showcased through computer-aided design (CAD) tasks, including the reconstruction of mechanical assemblies, as well as in building information modeling (BIM) tasks, which involve translating building outlines and specifications into detailed floor plans. Its hierarchical approach allows for parallel exploration of various design candidates, enhances the refinement of component geometries, and facilitates planning across numerous construction phases. Skyfall AI promotes SKY-001 as a research tool for applications in design and engineering, while also hinting at possible expansions into other areas of physical design. Those interested in utilizing this innovative tool can find a link to join a waitlist for future access on the product page, ensuring they remain updated on its public release. This model represents a significant step forward in the integration of artificial intelligence into practical design workflows.

API Access

Has API Yes 

API Access

Has API No 

Screenshots View All

Screenshots View All

No images available

Integrations

Biohub Yes 
Mira Yes 
Python Yes 

Integrations

Biohub No 
Mira No 
Python No 

Pricing Details

Free
Free Trial No 
Free Version Yes 

Pricing Details

No price information available.
Free Trial No 
Free Version No 

Deployment

Web-Based Yes 
On-Premises No 
iPhone App No 
iPad App No 
Android App No 
Windows No 
Mac No 
Linux No 
Chromebook No 

Deployment

Web-Based Yes 
On-Premises No 
iPhone App No 
iPad App No 
Android App No 
Windows No 
Mac No 
Linux No 
Chromebook No 

Customer Support

Business Hours No 
Live Rep (24/7) No 
Online Support Yes 

Customer Support

Business Hours No 
Live Rep (24/7) No 
Online Support No 

Types of Training

Training Docs Yes 
Webinars No 
Live Training (Online) No 
In Person No 

Types of Training

Training Docs No 
Webinars No 
Live Training (Online) No 
In Person No 

Vendor Details

Company Name

Biohub

Founded

2016

Country

United States

Website

biohub.ai/models/esmfold2

Vendor Details

Company Name

Skyfall AI

Founded

2024

Country

United States

Website

skyfall.ai/sky-001

Product Features

Product Features

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Alternatives

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