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Description
ESMFold2 builds upon its predecessor, ESMFold, by establishing a new benchmark in single-sequence structure prediction and facilitating the creation of novel functional proteins via exploration of the latent space within the ESMC model. This advanced model is capable of forecasting high-resolution, all-atom 3D structures of biomolecular complexes straight from the amino acid sequence, and it allows for the incorporation of multiple sequence alignments to improve accuracy on difficult targets. Tailored for predicting structures through both sequence and structure modalities, it employs ESM representations that drive a series of looped folding layers while a diffusion model translates pairwise representations into atomic-resolution outcomes. ESMFold2 excels in predicting protein structures from amino acid sequences, providing detailed structural data, including precise all-atom coordinates for both backbone and side chains, along with confidence metrics and optional distogram predictions for in-depth structural evaluation. Furthermore, its innovative approach enhances the understanding of protein folding dynamics and functional implications, making it a valuable tool for researchers in the field.
Description
Orbit BioSequence from Questel is an advanced tool for intellectual property (IP) intelligence, tailored to assist researchers, patent experts, and biotech firms in the thorough analysis and management of biological sequence data within the IP realm. This software presents a sophisticated framework for scrutinizing, analyzing, and keeping track of nucleotide and protein sequences identified in patent documents, thereby providing users with unprecedented access to vital sequence information that is essential for fostering innovation and conducting competitive assessments. With Orbit BioSequence, users can execute highly precise similarity and identity searches throughout international patent databases, empowering organizations to pinpoint existing patents, mitigate infringement risks, and discover potential licensing or collaboration opportunities. Furthermore, the software employs state-of-the-art search algorithms alongside meticulously curated datasets, guaranteeing both accuracy and relevance in the results. The comprehensive nature of this tool positions it as an invaluable resource in the evolving landscape of biotechnology and intellectual property management.
API Access
Has API
API Access
Has API
Integrations
Biohub
Python
Pricing Details
Free
Free Trial
Free Version
Pricing Details
No price information available.
Free Trial
Free Version
Deployment
Web-Based
On-Premises
iPhone App
iPad App
Android App
Windows
Mac
Linux
Chromebook
Deployment
Web-Based
On-Premises
iPhone App
iPad App
Android App
Windows
Mac
Linux
Chromebook
Customer Support
Business Hours
Live Rep (24/7)
Online Support
Customer Support
Business Hours
Live Rep (24/7)
Online Support
Types of Training
Training Docs
Webinars
Live Training (Online)
In Person
Types of Training
Training Docs
Webinars
Live Training (Online)
In Person
Vendor Details
Company Name
Biohub
Founded
2016
Country
United States
Website
biohub.ai/models/esmfold2
Vendor Details
Company Name
Questel
Country
France
Website
www.questel.com/patent/ip-intelligence-software/orbit-biosequence/