Average Ratings 0 Ratings
Average Ratings 0 Ratings
Description
ESMFold2 builds upon its predecessor, ESMFold, by establishing a new benchmark in single-sequence structure prediction and facilitating the creation of novel functional proteins via exploration of the latent space within the ESMC model. This advanced model is capable of forecasting high-resolution, all-atom 3D structures of biomolecular complexes straight from the amino acid sequence, and it allows for the incorporation of multiple sequence alignments to improve accuracy on difficult targets. Tailored for predicting structures through both sequence and structure modalities, it employs ESM representations that drive a series of looped folding layers while a diffusion model translates pairwise representations into atomic-resolution outcomes. ESMFold2 excels in predicting protein structures from amino acid sequences, providing detailed structural data, including precise all-atom coordinates for both backbone and side chains, along with confidence metrics and optional distogram predictions for in-depth structural evaluation. Furthermore, its innovative approach enhances the understanding of protein folding dynamics and functional implications, making it a valuable tool for researchers in the field.
Description
NVIDIA® Parabricks® stands out as the sole suite of genomic analysis applications that harnesses GPU acceleration to provide rapid and precise genome and exome analysis for various stakeholders, including sequencing centers, clinical teams, genomics researchers, and developers of high-throughput sequencing instruments. This innovative platform offers GPU-optimized versions of commonly utilized tools by computational biologists and bioinformaticians, leading to notably improved runtimes, enhanced workflow scalability, and reduced computing expenses. Spanning from FastQ files to Variant Call Format (VCF), NVIDIA Parabricks significantly boosts performance across diverse hardware setups featuring NVIDIA A100 Tensor Core GPUs. Researchers in genomics can benefit from accelerated processing throughout their entire analysis workflows, which includes stages such as alignment, sorting, and variant calling. With the deployment of additional GPUs, users can observe nearly linear scaling in computational speed when compared to traditional CPU-only systems, achieving acceleration rates of up to 107X. This remarkable efficiency makes NVIDIA Parabricks an essential tool for anyone involved in genomic analysis.
API Access
Has API
Yes
API Access
Has API
No
Integrations
Amazon Web Services (AWS)
No
Biohub
Yes
Google Cloud Platform
No
Microsoft Azure
No
Oracle Cloud Infrastructure
No
Python
Yes
Integrations
Amazon Web Services (AWS)
Yes
Biohub
No
Google Cloud Platform
Yes
Microsoft Azure
Yes
Oracle Cloud Infrastructure
Yes
Python
No
Pricing Details
Free
Free Trial
No
Free Version
Yes
Pricing Details
No price information available.
Free Trial
No
Free Version
No
Deployment
Web-Based
Yes
On-Premises
No
iPhone App
No
iPad App
No
Android App
No
Windows
No
Mac
No
Linux
No
Chromebook
No
Deployment
Web-Based
Yes
On-Premises
No
iPhone App
No
iPad App
No
Android App
No
Windows
No
Mac
No
Linux
No
Chromebook
No
Customer Support
Business Hours
No
Live Rep (24/7)
No
Online Support
Yes
Customer Support
Business Hours
No
Live Rep (24/7)
No
Online Support
Yes
Types of Training
Training Docs
Yes
Webinars
No
Live Training (Online)
No
In Person
No
Types of Training
Training Docs
Yes
Webinars
No
Live Training (Online)
No
In Person
No
Vendor Details
Company Name
Biohub
Founded
2016
Country
United States
Website
biohub.ai/models/esmfold2
Vendor Details
Company Name
NVIDIA
Founded
1993
Country
United States
Website
www.nvidia.com/en-us/clara/genomics/