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Description
ESMFold2 builds upon its predecessor, ESMFold, by establishing a new benchmark in single-sequence structure prediction and facilitating the creation of novel functional proteins via exploration of the latent space within the ESMC model. This advanced model is capable of forecasting high-resolution, all-atom 3D structures of biomolecular complexes straight from the amino acid sequence, and it allows for the incorporation of multiple sequence alignments to improve accuracy on difficult targets. Tailored for predicting structures through both sequence and structure modalities, it employs ESM representations that drive a series of looped folding layers while a diffusion model translates pairwise representations into atomic-resolution outcomes. ESMFold2 excels in predicting protein structures from amino acid sequences, providing detailed structural data, including precise all-atom coordinates for both backbone and side chains, along with confidence metrics and optional distogram predictions for in-depth structural evaluation. Furthermore, its innovative approach enhances the understanding of protein folding dynamics and functional implications, making it a valuable tool for researchers in the field.
Description
Microsoft has introduced Muse, an innovative generative AI model poised to transform the way gameplay concepts are developed. In partnership with Ninja Theory, this World and Human Action Model (WHAM) draws training data from the game Bleeding Edge, granting it a profound grasp of 3D game landscapes, including the intricacies of physics and player interactions. This capability allows Muse to generate varied and coherent gameplay sequences, which can enhance the creative process for developers. Additionally, the AI is capable of creating game visuals and anticipating controller actions, streamlining prototyping and artistic exploration in game design. By leveraging an analysis of over 1 billion images and actions, Muse showcases its potential not only for game creation but also for game preservation, as it can recreate classic titles for contemporary gaming platforms. Despite being in its initial phases, with output currently limited to a resolution of 300×180 pixels, Muse signifies a pivotal step forward in harnessing AI to support game development, with the goal of amplifying human creativity rather than supplanting it. As Muse evolves, it may open up new avenues for both game innovation and the revival of beloved gaming classics.
API Access
Has API
API Access
Has API
Integrations
Biohub
Claude Mythos 5
GPT-5.4 mini
GPT-5.4 nano
GPT-5.6
Hugging Face
Microsoft Foundry
Python
Integrations
Biohub
Claude Mythos 5
GPT-5.4 mini
GPT-5.4 nano
GPT-5.6
Hugging Face
Microsoft Foundry
Python
Pricing Details
Free
Free Trial
Free Version
Pricing Details
No price information available.
Free Trial
Free Version
Deployment
Web-Based
On-Premises
iPhone App
iPad App
Android App
Windows
Mac
Linux
Chromebook
Deployment
Web-Based
On-Premises
iPhone App
iPad App
Android App
Windows
Mac
Linux
Chromebook
Customer Support
Business Hours
Live Rep (24/7)
Online Support
Customer Support
Business Hours
Live Rep (24/7)
Online Support
Types of Training
Training Docs
Webinars
Live Training (Online)
In Person
Types of Training
Training Docs
Webinars
Live Training (Online)
In Person
Vendor Details
Company Name
Biohub
Founded
2016
Country
United States
Website
biohub.ai/models/esmfold2
Vendor Details
Company Name
Microsoft
Founded
1975
Country
United States
Website
microsoft.com