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Description
Differential Bio is an innovative virtual platform designed to enhance bioprocess optimization by making microbial growth more predictable, scalable, and economically viable, utilizing robotic laboratory automation and insights driven by artificial intelligence. The process initiates with automated, high-throughput experiments that replicate large-scale stress conditions within microliter settings, thereby producing relevant wet-lab data via liquid handling, fermentation, and measurement techniques. Tailored AI algorithms analyze this data to forecast various outcomes, including biomass growth, protein production, cell viability, titer, production rate, yield, and associated costs. Users can access the web-based platform to set their optimization targets and parameter limits, conduct limitless in-silico simulations, compare the results of simulated fermentation processes, engage in multi-objective optimization, and pinpoint the optimal conditions for scaling up production. This comprehensive approach not only streamlines the optimization workflow but also empowers teams to make data-informed decisions in bioprocess development.
Description
ESMFold2 builds upon its predecessor, ESMFold, by establishing a new benchmark in single-sequence structure prediction and facilitating the creation of novel functional proteins via exploration of the latent space within the ESMC model. This advanced model is capable of forecasting high-resolution, all-atom 3D structures of biomolecular complexes straight from the amino acid sequence, and it allows for the incorporation of multiple sequence alignments to improve accuracy on difficult targets. Tailored for predicting structures through both sequence and structure modalities, it employs ESM representations that drive a series of looped folding layers while a diffusion model translates pairwise representations into atomic-resolution outcomes. ESMFold2 excels in predicting protein structures from amino acid sequences, providing detailed structural data, including precise all-atom coordinates for both backbone and side chains, along with confidence metrics and optional distogram predictions for in-depth structural evaluation. Furthermore, its innovative approach enhances the understanding of protein folding dynamics and functional implications, making it a valuable tool for researchers in the field.
API Access
Has API
API Access
Has API
Integrations
Biohub
Python
Pricing Details
No price information available.
Free Trial
Free Version
Pricing Details
Free
Free Trial
Free Version
Deployment
Web-Based
On-Premises
iPhone App
iPad App
Android App
Windows
Mac
Linux
Chromebook
Deployment
Web-Based
On-Premises
iPhone App
iPad App
Android App
Windows
Mac
Linux
Chromebook
Customer Support
Business Hours
Live Rep (24/7)
Online Support
Customer Support
Business Hours
Live Rep (24/7)
Online Support
Types of Training
Training Docs
Webinars
Live Training (Online)
In Person
Types of Training
Training Docs
Webinars
Live Training (Online)
In Person
Vendor Details
Company Name
Differential Bio
Country
Germany
Website
www.differential.bio/
Vendor Details
Company Name
Biohub
Founded
2016
Country
United States
Website
biohub.ai/models/esmfold2