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Description

Claude Mythos 5 is a frontier AI model from Anthropic created for highly trusted users working on advanced cybersecurity, infrastructure protection, and scientific research. It is based on the same core model as Claude Fable 5, but certain safeguards are lifted for approved partners operating under restricted access programs. The model offers exceptional performance across software engineering, cybersecurity analysis, autonomous development workflows, scientific reasoning, visual understanding, and long-context tasks. In cybersecurity, Claude Mythos 5 is positioned for cyberdefenders and critical infrastructure providers who need advanced AI support for securing complex systems. In life sciences, the model has demonstrated strong capabilities in drug design, protein research, molecular biology, and genomics. Claude Mythos 5 can perform long-running research and technical workflows with minimal high-level human input. Anthropic designed the model for controlled deployment because its advanced capabilities could create misuse risks if broadly available without safeguards. Access is initially limited to Project Glasswing partners, with broader trusted access programs planned for cybersecurity and select biology researchers. Claude Mythos 5 helps approved organizations apply powerful AI to high-impact technical and scientific challenges while operating within a stricter governance model.

Description

ESMC represents the newest advancement in the ESM series of protein language models, pushing the boundaries of representation learning within the field of protein biology. With training on billions of evolutionary sequences, it adeptly captures representations that encapsulate a mechanistic understanding of protein structure and function. The model utilizes a transformer architecture, focusing on sequences as its primary modality, and is trained on a vast dataset comprising up to 6 billion proteins. ESMC is tailored for various protein science applications, such as predicting structures, annotating functions, designing proteins, and exploring evolutionary connections among proteins. Additionally, it possesses the capability to create novel proteins based on partial sequences, structures, or functional constraints, thereby enabling researchers to investigate innovative avenues in protein design and biological discovery. Accessible through the Biohub Platform, ESMC can be utilized via an API and the ESM Python package, which includes quickstart resources for installation, API key generation, and platform connectivity, ensuring a seamless experience for users. This comprehensive accessibility encourages a broader engagement with protein research and enhances collaborative efforts in the scientific community.

API Access

Has API Yes 

API Access

Has API Yes 

Screenshots View All

Screenshots View All

Integrations

Python Yes 
.NET Yes 
C# Yes 
C++ Yes 
Claude Desktop Yes 
Doraverse Yes 
Elixir Yes 
IntelliJ IDEA Yes 
Lovable Yes 
Model Context Protocol (MCP) Yes 
Muse Yes 
Objective-C Yes 
OpenClaw.Direct Yes 
Perplexity Pro Yes 
ReSharper Yes 
React Yes 
Revise Yes 
Springhub Yes 
Thread Deck Yes 
Trinity-Large-Thinking Yes 

Integrations

Python Yes 
.NET No 
C# No 
C++ No 
Claude Desktop No 
Doraverse No 
Elixir No 
IntelliJ IDEA No 
Lovable No 
Model Context Protocol (MCP) No 
Muse No 
Objective-C No 
OpenClaw.Direct No 
Perplexity Pro No 
ReSharper No 
React No 
Revise No 
Springhub No 
Thread Deck No 
Trinity-Large-Thinking No 

Pricing Details

$10 per 1 million (input)
$10 per million input tokens and $50 per million output tokens
Free Trial No 
Free Version No 

Pricing Details

Free
Free Trial No 
Free Version Yes 

Deployment

Web-Based Yes 
On-Premises No 
iPhone App No 
iPad App No 
Android App No 
Windows No 
Mac No 
Linux No 
Chromebook No 

Deployment

Web-Based Yes 
On-Premises No 
iPhone App No 
iPad App No 
Android App No 
Windows No 
Mac No 
Linux No 
Chromebook No 

Customer Support

Business Hours No 
Live Rep (24/7) No 
Online Support Yes 

Customer Support

Business Hours No 
Live Rep (24/7) No 
Online Support Yes 

Types of Training

Training Docs Yes 
Webinars No 
Live Training (Online) No 
In Person No 

Types of Training

Training Docs Yes 
Webinars No 
Live Training (Online) No 
In Person No 

Vendor Details

Company Name

Anthropic

Founded

2023

Country

United States

Website

claude.ai

Vendor Details

Company Name

Biohub

Founded

2016

Country

United States

Website

biohub.ai/models/esmc

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