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Average Ratings 0 Ratings

Total
ease
features
design
support

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Write a Review

Description

Aurora manages applications and services across a communal array of machines, ensuring their continuous operation. In the event of machine failures, Aurora adeptly reallocates those jobs to functioning machines. During job updates, it assesses the health and status of the deployment, automatically reverting changes if required. To ensure that certain applications receive guaranteed resources, Aurora employs a quota system and accommodates multiple users for service deployment. The services are highly customizable through a Domain-Specific Language (DSL) that facilitates templating, which helps in creating standard patterns and reducing repetitive configurations. Additionally, Aurora communicates the services to Apache ZooKeeper, enabling client discovery through tools like Finagle. This comprehensive approach allows for efficient management and deployment of services in a dynamic environment.

Description

Aurora utilizes principles of quantum mechanics and thermodynamics alongside a sophisticated continuous water model to assess the solvation effects on ligand binding affinities. This methodology is significantly different from the traditional scoring functions typically employed for predicting binding affinities. By integrating entropy and aqueous electrostatic contributions directly into the computations, Aurora's algorithms yield far more precise and reliable binding free energy values. The interaction between a ligand and a protein is fundamentally defined by the binding free energy value. This free energy (F) serves as a thermodynamic measure that correlates directly with the experimentally determined inhibition constant (IC50), influenced by factors such as electrostatic interactions, quantum effects, aqueous solvation forces, and the statistical characteristics of the molecules involved. Non-additivity in F arises primarily from two key components: the electrostatic and solvation energy, and the entropy, which together contribute to the complexity of ligand-protein interactions. Understanding these contributions is essential for the accurate prediction of binding affinities in drug design and molecular biology.

API Access

Has API

API Access

Has API

Screenshots View All

Screenshots View All

Integrations

Apache Mesos
Beats
Cloud Ops Group
Kapacitor
Paessler PRTG Hosted Monitor
cBackup

Integrations

Apache Mesos
Beats
Cloud Ops Group
Kapacitor
Paessler PRTG Hosted Monitor
cBackup

Pricing Details

No price information available.
Free Trial
Free Version

Pricing Details

No price information available.
Free Trial
Free Version

Deployment

Web-Based
On-Premises
iPhone App
iPad App
Android App
Windows
Mac
Linux
Chromebook

Deployment

Web-Based
On-Premises
iPhone App
iPad App
Android App
Windows
Mac
Linux
Chromebook

Customer Support

Business Hours
Live Rep (24/7)
Online Support

Customer Support

Business Hours
Live Rep (24/7)
Online Support

Types of Training

Training Docs
Webinars
Live Training (Online)
In Person

Types of Training

Training Docs
Webinars
Live Training (Online)
In Person

Vendor Details

Company Name

Apache Software Foundation

Founded

1999

Country

United States

Website

aurora.apache.org

Vendor Details

Company Name

Aurora Fine Chemicals

Founded

1990

Country

United States

Website

aurorafinechemicals.com/drug-discovery-software.html

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Product Features

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