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Description

ALBERT is a self-supervised Transformer architecture that undergoes pretraining on a vast dataset of English text, eliminating the need for manual annotations by employing an automated method to create inputs and corresponding labels from unprocessed text. This model is designed with two primary training objectives in mind. The first objective, known as Masked Language Modeling (MLM), involves randomly obscuring 15% of the words in a given sentence and challenging the model to accurately predict those masked words. This approach sets it apart from recurrent neural networks (RNNs) and autoregressive models such as GPT, as it enables ALBERT to capture bidirectional representations of sentences. The second training objective is Sentence Ordering Prediction (SOP), which focuses on the task of determining the correct sequence of two adjacent text segments during the pretraining phase. By incorporating these dual objectives, ALBERT enhances its understanding of language structure and contextual relationships. This innovative design contributes to its effectiveness in various natural language processing tasks.

Description

ESMFold2 builds upon its predecessor, ESMFold, by establishing a new benchmark in single-sequence structure prediction and facilitating the creation of novel functional proteins via exploration of the latent space within the ESMC model. This advanced model is capable of forecasting high-resolution, all-atom 3D structures of biomolecular complexes straight from the amino acid sequence, and it allows for the incorporation of multiple sequence alignments to improve accuracy on difficult targets. Tailored for predicting structures through both sequence and structure modalities, it employs ESM representations that drive a series of looped folding layers while a diffusion model translates pairwise representations into atomic-resolution outcomes. ESMFold2 excels in predicting protein structures from amino acid sequences, providing detailed structural data, including precise all-atom coordinates for both backbone and side chains, along with confidence metrics and optional distogram predictions for in-depth structural evaluation. Furthermore, its innovative approach enhances the understanding of protein folding dynamics and functional implications, making it a valuable tool for researchers in the field.

API Access

Has API No 

API Access

Has API Yes 

Screenshots View All

Screenshots View All

Integrations

Biohub No 
Python No 
Spark NLP Yes 

Integrations

Biohub Yes 
Python Yes 
Spark NLP No 

Pricing Details

No price information available.
Free Trial No 
Free Version No 

Pricing Details

Free
Free Trial No 
Free Version Yes 

Deployment

Web-Based Yes 
On-Premises No 
iPhone App No 
iPad App No 
Android App No 
Windows No 
Mac No 
Linux No 
Chromebook No 

Deployment

Web-Based Yes 
On-Premises No 
iPhone App No 
iPad App No 
Android App No 
Windows No 
Mac No 
Linux No 
Chromebook No 

Customer Support

Business Hours No 
Live Rep (24/7) No 
Online Support No 

Customer Support

Business Hours No 
Live Rep (24/7) No 
Online Support Yes 

Types of Training

Training Docs Yes 
Webinars No 
Live Training (Online) No 
In Person No 

Types of Training

Training Docs Yes 
Webinars No 
Live Training (Online) No 
In Person No 

Vendor Details

Company Name

Google

Founded

1998

Country

United States

Website

github.com/google-research/albert

Vendor Details

Company Name

Biohub

Founded

2016

Country

United States

Website

biohub.ai/models/esmfold2

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