Medicine

Anti-Aging Stem Cell Treatment Proves Successful In Early Human Trials (newatlas.com) 84

An anonymous reader quotes a report from New Atlas: The results of two human clinical trials into a stem cell therapy that can reverse symptoms of age-associated frailty have been published, and the indications are that this landmark treatment is both safe and strikingly effective in tackling key factors in aging. Mesenchymal stem cells (MSCs) are a particular type of adult stem cell generating a great deal of interest in the world of science. This new MSC treatment is targeted at reducing the effects of frailty on senior citizens. This is the first anti-aging stem cell treatment directed specifically at the problem of age-associated frailty to move close to a final FDA approval stage. The treatment derives human mesenchymal stem cells from adult donor bone marrow and in these clinical trials involves a single infusion in patients with an average age of 76. Both Phase 1 and Phase 2 human trials have demonstrated the treatment to have no adverse health effects.

Although the two human trials were ostensibly designed to just demonstrate safety they do offer remarkable results in efficacy as well, paving the way for larger, Phase 3 clinical trials. In the first trial 15 frail patients received a single MSC infusion collected from bone marrow donors aged between 20 and 45 years old. Six months later all patients demonstrated improved fitness outcomes, tumor necrosis factor levels and overall quality of life. The second trial was a randomized, double blind study with placebo group. Again no adverse affects were reported and physical improvements were noted by the researchers as "remarkable." The next stage for the research is to move into an expanded Phase 2b clinical trial involving 120 subjects across 10 locations. After that a final, large randomized Phase 3 clinical trial will be the only thing holding the treatment back from final public approval.
The results of the Phase 1 clinical trial were recently published in The Journals of Gerontology. The results of the Phase 2 clinical trial were recently published in The Journals of Gerontology. Further reading available via University of Miami, Miller School of Medicine.
Robotics

Sony Reportedly Announcing New Robot Dog Next Month (wsj.com) 45

Zorro shares a report from The Wall Street Journal (Warning: source may be paywalled; alternative source): Sony Corp. is planning next spring to roll out a dog-shaped pet robot similar to its discontinued Aibo with updated components that could allow it to control home appliances, people familiar with the matter said. Sony is preparing for a media event in November to show off the product, the people said. It is unclear whether the new product will use the Aibo name and how much it will cost. Sony Chief Executive Kazuo Hirai said last year at a strategy briefing that the company was developing "a robot capable of forming an emotional bond with customers, and able to grow to inspire love and affection." He told The Wall Street Journal at the time that the company might make an Aibo-like dog robot. The Nikkei newspaper reported earlier this month that Sony was targeting spring 2018 for the release of a home robot.
NASA

Astronaut Paul Weitz Dies At 85; Veteran of Skylab and Shuttle Missions 15

NPR reports the death of NASA astronaut Paul Weitz, who spent nearly a month in orbit on the first manned Skylab mission in 1973 and flew a decade later as mission commander on the maiden voyage of the Space Shuttle Challenger. He was 85. From the report: Weitz died in Flagstaff, Ariz., on Monday; he had been diagnosed with myelodysplastic syndrome, a type of blood cancer. Weitz was born in Erie, Pa., and graduated from Penn State. He joined the Navy and became an aviator and test pilot, eventually rising to the rank of captain. He was chosen in NASA's fifth round of astronaut selection in 1966, as the agency was ramping up for the Apollo moon program. On his first space flight, he served as pilot on Skylab-2 (SL-2), along with Apollo 12 veteran Charles "Pete" Conrad, Jr., and Joseph Kerwin, also a rookie on SL-2. The mission to fix Skylab, which had suffered significant damage during the space station's launch, is still considered one of the most difficult and dangerous in the annals of spaceflight. The three astronauts had to conduct multiple space walks to repair the damaged craft, deploying a giant reflective parasol to act as a sunshade in place of a damaged thermal shield. Weitz logged two hours and 11 minutes in space walks and the crew of the mission established a new world record for time in space -- 672 hours, 49 minutes.
Network

Legal Hack Back Lets You Go After Attackers In Your Network (csoonline.com) 47

itwbennett writes: Security startup Cymmetria has a new offering for customers: "legal hack back." The hack back tools have been added to the company's MazeHunter deception technology and will enable "tracking down the attack servers and wiping data originally stolen from their servers, probing the attack infrastructure for weaknesses to exploit, disabling the systems controlling malware, looking for information about the attackers to use in attribution, and launching distributed denial-of-service attacks to slow down criminal operations," but security teams are restricted to taking these actions on systems within their organizations, writes Fahmida Rashid in CSO Online. "Legal hack back via MazeHunter is more than traditional incident response because the organization can run a payload on the infected machine to engage with the attacker even before the forensics part of the investigation is complete," said Gadi Evron, founder and CEO of Cymmetria.
Government

Congress Opens Probe Into FBI's Handling of Clinton Email Investigation (arstechnica.com) 390

An anonymous reader quotes a report from Ars Technica: Two House committees announced Tuesday that they would conduct a joint probe into the FBI's handling of the Clinton e-mail investigation. The Clinton investigation concluded with no charges being levied against the former secretary of state who was running for president under the Democratic ticket. House Oversight and Government Reform Committee Chairman Trey Gowdy (R-S.C.) and House Judiciary Committee Chairman Bob Goodlatte (R-Va.) said in a joint statement that they are unsatisfied with how the probe into Clinton's private e-mail server concluded. Among other things, the chairmen want to know why the bureau publicly said it was investigating Clinton while keeping silent that it was looking into President Donald Trump's campaign associates and their connections to Russia.

"Our justice system is represented by a blind-folded woman holding a set of scales. Those scales do not tip to the right or the left; they do not recognize wealth, power, or social status," Goodlatte and Gowdy said in a joint statement. "The impartiality of our justice system is the bedrock of our republic, and our fellow citizens must have confidence in its objectivity, independence, and evenhandedness. The law is the most equalizing force in this country. No entity or individual is exempt from oversight."

Ubuntu

Why Did Ubuntu Drop Unity? Mark Shuttleworth Explains (omgubuntu.co.uk) 215

Ubuntu's decision to ditch Unity took many of us by surprise earlier this year. Now Ubuntu founder Mark Shuttleworth shares more details about why Ubuntu chose to drop Unity. From a report: Shuttleworth says he, along with the other 'leads' at Canonical, came to a consensual view that they should put the company on the path to becoming a public company. And to appear attractive to potential investors the company has to focus on its areas of profitability -- something Unity, Ubuntu phone, Unity 8 and convergence were not part of: "[The decision] meant that we couldn't have on our books (effectively) very substantial projects which clearly have no commercial angle to them at all. It doesn't mean that we would consider changing the terms of Ubuntu for example, because it's foundational to everything we do. And we don't have to, effectively," he said. Money may have meant Unity's demise but the wider Ubuntu project is in rude health. as Shuttleworth explains: "One of the things I'm most proud of is in the last 7 years is that Ubuntu itself became completely sustainable. I could get hit by a bus tomorrow and Ubuntu could continue. It's kind of magical, right? Here's a platform that is a world class enterprise platform, that's completely freely available, and yet it is sustainable. Jane Silber is largely to thank for that." While it's all-too-easy for desktop users to focus on, well, the desktop, there is far more to Canonical (the company) than the 6-monthly releases we look forward to. Losing Unity may have been a big blow for desktop users but it helped to balance other parts of the company: "There are huge possibilities for us in the enterprise beyond that, in terms of really defining how cloud infrastructure is built, how cloud applications are operated, and so on. And, in IoT, looking at that next wave of possibility, innovators creating stuff on IoT. And all of that is ample for us to essentially put ourselves on course to IPO around that." Dropping Unity wasn't easy for Mark, though: "We had this big chunk of work, which was Unity, which I really loved. I think the engineering of Unity 8 was pretty spectacularly good, and the deep ideas of how you bring these different form factors together was pretty beautiful.
Businesses

Google Launches Gmail Add-ons and Brings a Range of Business Tools To the Inbox (betanews.com) 64

Google today launched Gmail Add-ons after a beta testing period as a developer preview earlier in the year. From a report: Gmail Add-ons are extensions that bring a number of big-name services -- such as Trello, Wrike and Asana -- to your inbox. While there's a definite business and enterprise bias, it's something that available to everyone, starting right now. The arrival of Gmail Add-ons is Google's recognition of the fact that many people now spend a huge amount of time in their inboxes, and the company is trying to make its email service even more useful. Pleasingly, add-ons are available on both the web and on Android, and Google explains that "your inbox can contextually surface your go-to app based on messages you receive to help you get things done faster."
Bitcoin

TV News 'Hack' Sees Bitcoins Swiped (bbc.com) 33

Two French hackers used their computer skills to reconstruct a blurred-out code on TV and claim bitcoins worth $1,000. From a report: Michel Sassano and Clement Storck had seen an interview with entrepreneur Roger Ver on French television. Mr Ver had offered $1,000 to viewers - but a QR code needed to claim the money had been blurred out. The duo analysed a small part of the code that was visible, however, and managed to access the funds. When the France 2 channel broadcast its interview with Mr Ver earlier this month, he promised the money -- just over three bitcoin cash coins, worth $1,000 -- to whichever viewer was quickest to scan an on-screen QR code. However, the code had been blurred out by France 2 -- Mr Sassano believes this is because of French broadcasting regulations that prevent news programmes from giving away prizes. "The process to decode the private key from the moment we watched the show to when we entered it in the wallet took, I think, between 12 and 16 hours," Mr Sassano told the BBC.
Education

42% of Americans Under 8 Have Their Own Tablet (axios.com) 221

A reader shares an Axios report: A whopping 42% of children ages 0-8 have their own tablet device, up from less than 1% in 2011, according to Common Sense Media's newest national "Media Use by Kids" census. Families with young children are now more likely to have a subscription video service such as Netflix or Hulu (72%) than they are to have cable TV (65%). 10% of kids age 8 or under own a "smart" toy that connects to the internet and 9% have a voice-activated virtual assistant device available to them in the home, such as an Amazon Echo or Google Home.
Bitcoin

Bitcoin Pioneer Says New Coin To Work on Many Blockchains (bloomberg.com) 65

A reader shares a Bloomberg report: Jeff Garzik, one of a handful of key developers who helped build the underlying software for bitcoin that is known as blockchain, has seen its shortcomings firsthand. So he decided to create a better digital currency. He's calling it Metronome and says it will be the first that can jump between different blockchains. For example, coins that are used for applications on the Ethereum blockchain will be able to move to Ethereum Classic before jumping onto Qtum or Rootstock, which connects with the bitcoin blockchain, said Garzik. The mobility means that if one blockchain dies out as the result of infighting among developers or slackened use, metronome owners can move their holdings elsewhere. That should help the coins retain value, and ensure their longevity, Garzik, co-founder of startup Bloq that created metronome, said in a phone interview. It will be unveiled Tuesday at the Money 20/20 conference in Las Vegas. "Institutional investors should be very excited to see something like this," Matthew Roszak, the other co-founder of Bloq and chairman of industry advocate Chamber of Digital Commerce, said in a phone interview. "We've built a thousand-year cryptocurrency, something that's built to last." That's a concern for many digital currencies. Infighting among developers and various supporters, and the slow pace of enhancements on the bitcoin blockchain have helped to limit use. Both bitcoin and its main rival, ethereum, have split into several versions.
Government

New Cyber Attacks Hit Airport, Metro in Ukraine (reuters.com) 50

Cyber attacks hit Ukraine's Odessa airport and the metro system in Kiev on Tuesday, with the state-run Computer Emergency Response Team (CERT) saying a new wave of hacks was hitting the country and asking transport networks to be on particular alert. From a report: Ukraine was the chief victim of a major cyber attack earlier this year, and the government had warned on Oct. 13 that another strike might be coming. "We ask the owners of telecommunication systems, other information resources, transport infrastructure first of all, as well as ordinary internet users, to comply with stricter cyber security requirements," CERT-Ukraine said in a statement. The cyber police and the infrastructure ministry said that Tuesday's strikes did not appear to constitute a mass attack. The central bank said the banking system was working normally. "We report that the IT system of Odessa international airport has been hit by a hacker attack. All services of the airport are working in a stricter mode," the airport said in a statement.
Businesses

WeWork Employees Caught Spying on Competition (nypost.com) 112

An anonymous reader shares a report: The battle in the red-hot co-working space business is heating up. WeWork, the No. 1 player in the sector, allegedly sent two spies to infiltrate rival Knotel -- to steal info and some customers, Knotel claimed. The spies showed up at seven Knotel properties in Manhattan last month in a "systematic attempt to pilfer Knotel's proprietary information and trade secrets," according to a cease-and-desist letter the smaller company sent to WeWork. The Post has obtained a copy of the letter. The corporate espionage rookies may have pulled off the caper except, in a totally random happening, a Knotel employee recognized one of them as a friend of a friend, according to sources close to Knotel. While the pair used fake names to gain entry, according to the letter, a call to the Knotel worker's pal got the spy's real name -- and a couple of social media inquiries turned up the fact that he worked for rival WeWork, sources said. The letter to WeWork asks for a reply by Oct. 13 -- but so far Knotel hasn't heard a peep from its rival, according to CEO Amol Sarva. While inside the Knotel offices, visited Sept. 12-14, the luckless spies posed "as the founders of a fast-growing startup" and said they needed space for their six-person company, according to the letter.
Microsoft

Microsoft To Drop Lawsuit After US Government Revises Data Request Rules (reuters.com) 28

An anonymous reader shares a report: Microsoft said it will drop a lawsuit against the U.S. government after the Department of Justice (DOJ) changed data request rules on alerting internet users about agencies accessing their information. The new policy limits the use of secrecy orders and calls for such orders to be issued for defined periods, Microsoft Chief Legal Officer Brad Smith said in a blog post on Monday. "As a result of the issuance of this policy, we are taking steps to dismiss our lawsuit," Smith said. The company expects the changes to end the practice of indefinite secrecy orders. Microsoft filed the lawsuit in April 2016 arguing that the U.S. government was violating the constitution by preventing the company from informing its customers about government requests for their emails and other documents.
AI

Tech Giants Are Paying Huge Salaries For Scarce AI Talent (santafenewmexican.com) 156

jmcbain writes: Machine learning and artificial intelligence skills are in hot demand right now, and it's driving up the already-high salaries in Silicon Valley. "Tech's biggest companies are placing huge bets on artificial intelligence (Warning: may be paywalled; alternative source)," reports the New York Times, and "typical AI specialists, including both Ph.D.s fresh out of school and people with less education and just a few years of experience, can be paid from $300,000 to $500,000 a year or more in salary and company stock." The New York Times notes there are several catalysts for rocketing salaries that all come down to supply and demand. There is competition among the giant companies (e.g. Google, Facebook, and Uber) as well as the automative companies wanting help with self-driving cars. However, the biggest issue is the supply: "Most of all, there is a shortage of talent, and the big companies are trying to land as much of it as they can. Solving tough A.I. problems is not like building the flavor-of-the-month smartphone app. In the entire world, fewer than 10,000 people have the skills necessary to tackle serious artificial intelligence research, according to Element AI, an independent lab in Montreal."
Facebook

Tech Firms Seek Washington's Prized Asset: Top-Secret Clearances (bloomberg.com) 147

Major tech companies such as Facebook and Twitter are interested in hiring workers with top-secret security clearances as they deal with foreign meddling on their platforms and come under increased risk of hacks, reports Bloomberg. From the article: In doing so, companies such as Facebook are competing with defense contractors, financial firms and the U.S. government itself. Security clearances are a rare and valued commodity, whether at a bank trying to prevent hackers from stealing credit-card data and emptying accounts or at a manufacturer building parts for a stealth fighter or missile-defense radar system. Bringing former government cyber warriors on board at companies can facilitate interactions with U.S. agencies like the NSA or CIA as well as help the firms understand how to build stronger systems on their own. "They have the tradecraft," said Ronald Sanders, a former associate director of the Office of the Director of National Intelligence and now director of the school of public affairs at the University of South Florida. "And the trade craft is some of the best in the world."

Slashdot Top Deals