The HUP is more fundamental than that. It doesn't just say that we can't know where a particle is because measurement disturbs it; rather it's telling you that the particle actually doesn't have a definite trajectory. In fact, it's so fundamental that it has its own mathematical formalism (commutativity of operators), upon which most of quantum mechanics is constructed.
It's important to realize that in quantum mechanics, the position of a particle is indefinite, and is specified by a diffuse/spread-out "cloud" probability, and only in special cases does this cloud collapse to a single point (which corresponds to the particle being in a definite place).
Note that it is possible (theoretically) to know the position or momentum of a particle, just not at the same time, since measuring one causes the other to become indeterminate.
Doubt is a pain too lonely to know that faith is his twin brother. - Kahlil Gibran