Comment I've been there - NTFS all the way (Score 2, Interesting) 484
I have been through exactly the same thing, and NTFS is the way to go. My main machine is a Mac, but I format all my USB drives as NFTS (through NTFS-3G FUSE). Though this is slower than formating as FAT or HFS+, it is so much more portable, it wins out.
Windows machines can read them.
My WD TV box can read them.
My Mac can read them.
They can store more than 4G per file (indeed, I have all my DVD isos on them).
Ok, they can't be read on other macs without installing NTFS-3G, but I've yet to need that.
For me, I've never had any problem with NTFS-3G , it's extremely reliable.