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Comment Re:Wrong problem (Score 1) 239

So the difficulty is to arrange those strips to reproduce the original DNA sequence. It is a NP-hard problem, no wonder Moore's law doesn't outrun that!

What does that even mean? The length of a human genome is for all practical purposes fixed, so scaling is utterly irrelevant. .

Who says were just (re)sequencing the Human genome? There are plenty of Model Organisms in the pipeline. Then there are the things like the Human microbiome project

Comment Re:Wrong problem (Score 2) 239

The internet needs to catch up first.

At my Uni I can get ~80Mbps download 40Mbps upload speed. One high throughput sequencer can generate ~700GB/day (1) so it would take 1.6 days to upload 1 days worth of data. For a small lab it may just be possible in improve the upload speed enough to get by on. But with little to no margin of downtime.

(1) this data can be discarded after analysis but needs to be retained for at least 2-3 months in case a reanalysis is needed

Comment Re:The Truth (Score 1) 83

It can be hard to break into (but well worth it) alas I can only provide a UK perspective but I suspect its valid elsewhere

The main problem is finding people to game with options include

  • finding a (physical) games shop and seeing it it has a players wanted board
  • googling for phrases like 'games day' 'games fest' 'games convention' 'games club|soc|society'
  • if there is a local university, collage or similar see if they have a games soc.

one really radical solution is to start your own games day!! I go to one that was started by a guy who wanted to play games but didn't have any so he advertised a games day. For the first few meets you need somewhere free but with luck you have an entry fee and hire a hall.

The main thing to remember is that you may need to kiss a lot of frogs before you find your perfect group. There are a lot of styles of play from the hyper stimulationist where they endlessly discuss agrarian economics and the effects that low level magic usage would have on it, to group that likes to hang out and crack poor quality jokes

try reading GM of the Rings and Darths and Droids to get a idea of different play styles (I'd give my eye teeth to be in the Darths and Droids group!!!)

Comment Re:Not totally suprised (Score 1) 121

"Oh Dad I'm still playing it and if you pull the plug I'll lose all the virtual toys that I've built up"

I would be very surprised if cancelling an account deleted all progress. In every MMO I've ever played you can cancel your account and go back years later and pick up right where you left off. This is a big marketing tool for bringing players back, if you had to start from scratch every time then once players cancelled there would be pretty much no chance of getting them to resubscribe.

Its not much better...

"So Son thanks to MrAngryForNoReason, You can keep your toys, but there locked up in that cupboard over there. If you want to play with them you will have to pay a week and a half's pocket money to get at them and you must give the key back after a month."

Comment Not totally suprised (Score 0) 121

As a parent the subscription shouted "MMO money sink avoid". I'd guess my son would play furiously in the first month, heavily in second, then sporadically after that. It was the final phase that worried me. "Oh Dad I'm still playing it and if you pull the plug I'll lose all the virtual toys that I've built up". I think he has a point he has worked for it(1) why can't he keep it? Basically it would become a White elephant in the purest sense...

Much better to buy him one of the excellent LEGO <Movie Title>: The Video Game series, which can be kept and played more or less indefinitely.

(1) in some way shape or form at the very least the investment of time.

Comment Re:Do the work before they pay you for it (Score 1) 283

You have some time though, so I'd suggest you get a hobby in the field you're going into. Help out some open source rocketry projects. Surely they exist. Launch some things up really high. Rig up some cameras and get pictures. Write some code. etc. etc.

This advice is widely applicable, Begin able to talk about your home automation/IT project, your latest Make or other cool project in CV and interview can really set you apart from the competition. as it portrays you as an enthusiastic, self starter who does the work because they like it rather than a jaded code wrangler who does it 9-5 for the money.

Comment Re:Vaccines != Antibiotics (Score 1) 147

True but vaccines train the body to recognise markers so one presumes that a strain of malaria may arise without the markers that are recognised.

Possibly, the big achievement is find anything to target. malarias coat proteins are highly polymorphic to better avoid the immune system and all the stable stuff is hidden under the coat protein.

If a resistant strain does become prevalent it should be possible to create a vaccine against that

Comment Re:Malaria seems to be adaptable (Score 1) 147

True but vaccines train the body to recognise markers so one presumes that a strain of malaria may arise without the markers that are recognised.

Possibly, the big achievement is find anything to target. malarias coat proteins are highly polymorphic to better avoid the immune system and all the stable stuff is hidden under the coat protein.

If a resistant strain does become prevalent it should be possible to create a vaccine against that targeting the same protein.

Comment Re:Somebody tell the schools (Score 2) 184

So they can call for help if they have problems getting home. Very useful in more rural areas. My local primary school is about 200 meters away, so perhaps not so useful in a large town.

This. Our boy has had one since he was 10 but didn't use it much till he went to secondary school.

Has locked himself out twice (second time he phoned to ask where the spare key was hidden:-). He hasn't missed the school bus yet but its only a matter of time, Coming back from school trips to say when he's actually getting back as a pose to when he's scheduled to get back. If we get separated (deliberately on not) in town its useful to reorganize a meet-up point.

This is not helicopter parenting, its just maintaining a basic level of communication. Its the simple things like being able to call ahead and say were going to be late that make it worth every penny.

Comment Re:about freaking time! (Score 1) 212

You should have said windows 3.1, or windows for workgroups. Just to see what the hell they would do.

Next time they ring I'm planning spend 20-30 minutes doing something like this.

A computer running slow? Oh yes I have I'm really glad you called... I'll just boot it up.... (sound FX of me wandering round the house) turn it on.. Oh its not working... (more faffing round) Oops it was unplugged... OK Booting ... booting... OK I've got the prompt w... i... n.... OK its starting ... starting .... starting Argh Its bluescreened its a very poorly puppy I'm glad of your help. I'll try again (on the third attempt) OK I'm in windows just start up Mosaic it sometimes takes a couple of minutes... whats the weather like at your end? (after a few other network problems) OK I've downloaded your program double clicked on it Oh I've got an error saying that this is a 32 bit program and won't run on a 16 bit system ... do you have one that supports Windows 3.1?

Comment Re:This... Perhaps (Score 1) 264

Had second thoughts about £4000 lasting long enough. If they can find a service that costs ~15p/hour (and it seems reasonable that they could) that would provide 24/7 computing power for a 3 year grant and better than that, any unused time/money could be kept and used on special occasions/rush jobs...

The point about restrictions on how the grant is spent still stand though :-(

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