Comment Re:How to conduct human trials (Score 1) 190
Why would you not expect all of the participants to (statistically speaking) modify their behaviour in the same way? If the people who get the real anti-HIV drug modify, and the people who get the placebo modify then the chances are good that the modifications will be evenly spread with a large enough sample pool. If, given the modified behaviour, the HIV drug performs with statistically meaningful results then you have a positive result from the study.