I do set up networks. I'm not being lazy, I'm being pragmatic. IP4 is easy to work because most people can look at an ip address and break it down to 4 numbers; 4 tokens to remember for the few moments when it needs to be remembered. I'm sure there are people practiced with hexidecimal that will find it very easy to work with, but for most techs a 4 character string of hexidecimal is not an instantly recognizable number, it's a quazi-random string of characters. This is mostly an issue of practice and language skills. The number 746, for example, in hex is 2A1. 746 is easy to remember by saying seven hundred and fourty six. Mentally it is one number. 2A1 does not have any ingrained meaning to most people because most people have not been practicing with hex their entire lives.
I wager that the decision to use Hex will cause a great number of mistakes that would not have happened with a decimal-based notation system. I also wager that this will cause a measurable increase in the amount of time it takes to set up networks because it will flat out take longer to transpose numbers, triple check them, and correct the increased number of errors. In manufacturing, when a large number of errors or accidents happen at one stage of the line, it is because the process is flawed. I believe this will go down in history a significant flaw that causes many errors and waste a lot of time.