Addicting Mice To Light 92
Al writes "In an attempt to better understand how the reward system in the brain functions in people suffering from addiction, scientists at Stanford have created mice that are addicted to light. They engineered light-sensitive proteins to trigger signaling pathways in the nucleus accumbens, a part of the brain that responds to pleasurable stimuli. They then connected a fiber-optic cable to this part of the brain and delivered a blast of light whenever the mice wandered into a 'reward chamber.' In previous experiments the mice have been given drugs like cocaine or amphetamine when they enter these rooms. The light treatment works in exactly the same way but lets the researchers very precisely control timing and dose of reward administered to the brain. The approach could also provide a way to probe receptors that cannot be accessed using existing drugs."