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The Manga Guide to Statistics 164

stoolpigeon writes "Many manga titles that are popular in Japan are being translated into English and published in the United States. This trend continues with a book that puts a slightly different spin on manga. The Manga Guide to Statistics, part of a series already popular in Japan, seeks to entertain while it informs. There are many elements here that can be found in any manga; a young love-struck girl, giant eyes, small noses and exaggerated emotional responses. What many may not have seen in manga before are things like calculating the mean, median and deviation of bowling scores. And that is just the start." Read below for the rest of JR's review.

Comment Re:Not realistic (Score 1) 198

You always have to be skeptical when an institute pushes news of a discovery that has not been published yet. There are definitely inherent problems with current stem cell work (embryonic and non-embryonic), but we're getting better. However I don't think we've even thought about the largest hurdles and how to get over them. The biggest problem I see with this and other stem cell work is it involves transforming cells with multiple genes (often these genes are integrated into the host genome) which a number of them are usually potent oncogenes (c-myc is a good example used often). The result you typically get is a cell with similar phenotype to the tissue that the researcher is trying to grow, but these cells often aren't normal karyotypically. Karyotypic change is one of (if not the major) driving force of tumorigenesis and is involved in a number of other diseases, but most of the stem cell labs never check karyotypes. They are always assumed to be normal when they aren't. Unstable karyotypes are one of the reasons that embryonic stem cell research has been problematic. For some reason, when put into culture especially for extended periods of time embryonic stem cells are less stable than somatic stem cells. Hence embryonic stem cell therapy often results in cancer.

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